Machine Learning Methods in Health Economics and Outcomes Research-The PALISADE Checklist : A Good Practices Report of an ISPOR Task Force

Copyright © 2022. Published by Elsevier Inc..

Advances in machine learning (ML) and artificial intelligence offer tremendous potential benefits to patients. Predictive analytics using ML are already widely used in healthcare operations and care delivery, but how can ML be used for health economics and outcomes research (HEOR)? To answer this question, ISPOR established an emerging good practices task force for the application of ML in HEOR. The task force identified 5 methodological areas where ML could enhance HEOR: (1) cohort selection, identifying samples with greater specificity with respect to inclusion criteria; (2) identification of independent predictors and covariates of health outcomes; (3) predictive analytics of health outcomes, including those that are high cost or life threatening; (4) causal inference through methods, such as targeted maximum likelihood estimation or double-debiased estimation-helping to produce reliable evidence more quickly; and (5) application of ML to the development of economic models to reduce structural, parameter, and sampling uncertainty in cost-effectiveness analysis. Overall, ML facilitates HEOR through the meaningful and efficient analysis of big data. Nevertheless, a lack of transparency on how ML methods deliver solutions to feature selection and predictive analytics, especially in unsupervised circumstances, increases risk to providers and other decision makers in using ML results. To examine whether ML offers a useful and transparent solution to healthcare analytics, the task force developed the PALISADE Checklist. It is a guide for balancing the many potential applications of ML with the need for transparency in methods development and findings.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:25

Enthalten in:

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research - 25(2022), 7 vom: 02. Juli, Seite 1063-1080

Sprache:

Englisch

Beteiligte Personen:

Padula, William V [VerfasserIn]
Kreif, Noemi [VerfasserIn]
Vanness, David J [VerfasserIn]
Adamson, Blythe [VerfasserIn]
Rueda, Juan-David [VerfasserIn]
Felizzi, Federico [VerfasserIn]
Jonsson, Pall [VerfasserIn]
IJzerman, Maarten J [VerfasserIn]
Butte, Atul [VerfasserIn]
Crown, William [VerfasserIn]

Links:

Volltext

Themen:

Artificial intelligence
Journal Article
Machine learning
Research Support, N.I.H., Extramural

Anmerkungen:

Date Completed 07.07.2022

Date Revised 19.08.2022

published: Print

Citation Status MEDLINE

doi:

10.1016/j.jval.2022.03.022

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM343006901