Features and evolution of patients with COVID-19 who required mechanical ventilation
BACKGROUND: The overall mortality of patients with COVID-19 admitted to intensive care units is approximately 40%.
AIM: To describe the characteristics of a cohort of patients with COVID-19 who required invasive mechanical ventilation due to severe hypoxemic acute respiratory failure at a general hospital in Santiago, Chile.
MATERIAL AND METHODS: Review of medical records and follow up for 28 days of patients with COVID-19 confirmed by polymerase chain reaction who required invasive mechanical ventilation and who were admitted to the intensive care unit from March 24 to June 7, 2020.
RESULTS: Data from 152 patients aged 58 (interquartile range (IQR) 47-65 years (66% men) was analyzed. As of July 5, 36 (24%) had died, 75 (49%) were discharged, 10 (7%) were still on invasive mechanical ventilation, 11 (7%) remained with tracheostomy but without invasive mechanical ventilation, and 20 (13%) were hospitalized in a basic unit. The median time on invasive mechanical ventilation among extubated patients was 14 days (IQR 10-21) and 121 (80%) were in the prone position. Patients who died were older, had a higher frequency of diabetes mellitus and a higher driving pressure at 7 days than those discharged alive from the intensive care unit.
CONCLUSIONS: In this study mortality was lower than that reported in the first international studies, probably due to the selection of younger patients and greater knowledge of the disease.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:149 |
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| Enthalten in: |
Revista medica de Chile - 149(2021), 11 vom: 30. Nov., Seite 1544-1551 |
| Sprache: |
Spanisch |
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| Weiterer Titel: |
Características y resultados de pacientes COVID-19 tratados con ventilación mecánica invasiva en Hospital San Juan de Dios. Marzo-junio 2020 |
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| Beteiligte Personen: |
Navarrete M, Wilfredo [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Completed 24.06.2022 Date Revised 24.06.2022 published: Print Citation Status MEDLINE |
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| doi: |
10.4067/S0034-98872021001101544 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM342564528 |
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| 245 | 1 | 0 | |a Features and evolution of patients with COVID-19 who required mechanical ventilation |
| 246 | 3 | 3 | |a Características y resultados de pacientes COVID-19 tratados con ventilación mecánica invasiva en Hospital San Juan de Dios. Marzo-junio 2020 |
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| 500 | |a Date Completed 24.06.2022 | ||
| 500 | |a Date Revised 24.06.2022 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: The overall mortality of patients with COVID-19 admitted to intensive care units is approximately 40% | ||
| 520 | |a AIM: To describe the characteristics of a cohort of patients with COVID-19 who required invasive mechanical ventilation due to severe hypoxemic acute respiratory failure at a general hospital in Santiago, Chile | ||
| 520 | |a MATERIAL AND METHODS: Review of medical records and follow up for 28 days of patients with COVID-19 confirmed by polymerase chain reaction who required invasive mechanical ventilation and who were admitted to the intensive care unit from March 24 to June 7, 2020 | ||
| 520 | |a RESULTS: Data from 152 patients aged 58 (interquartile range (IQR) 47-65 years (66% men) was analyzed. As of July 5, 36 (24%) had died, 75 (49%) were discharged, 10 (7%) were still on invasive mechanical ventilation, 11 (7%) remained with tracheostomy but without invasive mechanical ventilation, and 20 (13%) were hospitalized in a basic unit. The median time on invasive mechanical ventilation among extubated patients was 14 days (IQR 10-21) and 121 (80%) were in the prone position. Patients who died were older, had a higher frequency of diabetes mellitus and a higher driving pressure at 7 days than those discharged alive from the intensive care unit | ||
| 520 | |a CONCLUSIONS: In this study mortality was lower than that reported in the first international studies, probably due to the selection of younger patients and greater knowledge of the disease | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Miranda S, Daniel |e verfasserin |4 aut | |
| 700 | 1 | |a Briceño M, Gonzalo |e verfasserin |4 aut | |
| 700 | 1 | |a Gramusset H, Lissette |e verfasserin |4 aut | |
| 700 | 1 | |a Allende C, Miguel |e verfasserin |4 aut | |
| 700 | 1 | |a Céspedes M, Natalia |e verfasserin |4 aut | |
| 700 | 1 | |a Pizarro L, Nicolás |e verfasserin |4 aut | |
| 700 | 1 | |a Bravo B, Felipe |e verfasserin |4 aut | |
| 700 | 1 | |a González B, Sandra |e verfasserin |4 aut | |
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