Extrapulmonary Small Cell Carcinoma Presenting as an Orbital Mass : A Case Report
Copyright © 2022, Meinhardt et al..
Extrapulmonary small cell carcinomas (ESCCs) are poorly differentiated neuroendocrine tumors that are characterized by an aggressive course and poor survival rates. While these tumors can be found anywhere in the body, presentations of lesions in the orbit are exceedingly rare. We present the case of a 47-year-old man who presented with blurry vision, lacrimation, and tenderness of his right eye, as well as a small but palpable temporal mass. Upon workup, he was diagnosed with ESCC in the orbit as well as lesions in the liver and spine. He received systemic chemotherapy but unfortunately proceeded to have rapid spread of his disease and succumbed to this cancer only a year after presentation. This patient illustrates the importance of developing optimal treatment strategies, which have yet to be delineated, and especially the impact of newer immunotherapy agents remains to be seen.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2022 |
---|---|
Erschienen: |
2022 |
Enthalten in: |
Zur Gesamtaufnahme - volume:14 |
---|---|
Enthalten in: |
Cureus - 14(2022), 6 vom: 17. Juni, Seite e26012 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Meinhardt, Anna-Lena [VerfasserIn] |
---|
Links: |
---|
Themen: |
Case Reports |
---|
Anmerkungen: |
Date Revised 16.07.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
---|
doi: |
10.7759/cureus.26012 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM342551736 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM342551736 | ||
003 | DE-627 | ||
005 | 20231226014359.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231226s2022 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.7759/cureus.26012 |2 doi | |
028 | 5 | 2 | |a pubmed24n1141.xml |
035 | |a (DE-627)NLM342551736 | ||
035 | |a (NLM)35734026 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Meinhardt, Anna-Lena |e verfasserin |4 aut | |
245 | 1 | 0 | |a Extrapulmonary Small Cell Carcinoma Presenting as an Orbital Mass |b A Case Report |
264 | 1 | |c 2022 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Revised 16.07.2022 | ||
500 | |a published: Electronic-eCollection | ||
500 | |a Citation Status PubMed-not-MEDLINE | ||
520 | |a Copyright © 2022, Meinhardt et al. | ||
520 | |a Extrapulmonary small cell carcinomas (ESCCs) are poorly differentiated neuroendocrine tumors that are characterized by an aggressive course and poor survival rates. While these tumors can be found anywhere in the body, presentations of lesions in the orbit are exceedingly rare. We present the case of a 47-year-old man who presented with blurry vision, lacrimation, and tenderness of his right eye, as well as a small but palpable temporal mass. Upon workup, he was diagnosed with ESCC in the orbit as well as lesions in the liver and spine. He received systemic chemotherapy but unfortunately proceeded to have rapid spread of his disease and succumbed to this cancer only a year after presentation. This patient illustrates the importance of developing optimal treatment strategies, which have yet to be delineated, and especially the impact of newer immunotherapy agents remains to be seen | ||
650 | 4 | |a Case Reports | |
650 | 4 | |a episcleritis | |
650 | 4 | |a extrapulmonary small cell carcinoma | |
650 | 4 | |a intra orbital mass | |
650 | 4 | |a neuroendocrine neoplasm | |
650 | 4 | |a orbital malignancy | |
650 | 4 | |a small cell carcinoma | |
700 | 1 | |a Uppuluri, Aditya |e verfasserin |4 aut | |
700 | 1 | |a Shkolnik, Elina |e verfasserin |4 aut | |
700 | 1 | |a Chang, Victor T |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Cureus |d 2013 |g 14(2022), 6 vom: 17. Juni, Seite e26012 |w (DE-627)NLM24118083X |x 2168-8184 |7 nnns |
773 | 1 | 8 | |g volume:14 |g year:2022 |g number:6 |g day:17 |g month:06 |g pages:e26012 |
856 | 4 | 0 | |u http://dx.doi.org/10.7759/cureus.26012 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 14 |j 2022 |e 6 |b 17 |c 06 |h e26012 |