Relationship between lifestyle factors and hypertension : a cross-sectional analysis from the Gubbio study
BACKGROUND: Hypertension (HTN) is a well-established and a major risk factor for cardiovascular disease. Lifestyle behaviours for its prevention and control are recommended within worldwide guidelines. Their relationship with HTN need more investigations.
AIM: We aimed to investigate the associations between lifestyle, anthropometric and biological measurements and BP in the Gubbio residential study.
METHODS: Cross-sectional analyses were performed using data from Gubbio study. Information concerning lifestyle factors were collected using self-reported questionnaire and were further completed with a baseline clinical examination and blood exams. Three BP measurements were performed following a standard protocol. Age-adjusted and multivariable logistic regressions were used to examine the relationships between lifestyle parameters and HTN separately for each sex. We used heterogeneity test to observe sex differences.
RESULTS: There were 3,183 persons included (48% men, 43 ± 17 years old). Mean systolic BP (SBP) was 119 ± 16 mmHg and 10.6% were hypertensives. Age [OR: 129.70 (95%CI: 18.57-905.79) in women and OR: 8.37 (95%CI: 4.01-17.48) (p < 0.0001) in men] and BMI [OR: 2.14 (95%CI: 1.32-3.46) (p = 0.006) in women and OR: 1.81 (95%CI: 1.05-3.12), p = 0.03 in men], were positively associated with SBP in both sexes. Serum uric acid [OR: 3.86 (95%CI: 2.03-7.26), p = 0.04] was positively associated with HTN in women while fasting blood glucose [OR: 3.04 (95%CI: 1.55-5.97), p < 0.001] were associated to HTN only in men.
DISCUSSION: In addition to age, BMI is associated with HTN in both sexes while sex differences were observed in the associations between serum uric acid, fasting blood glucose and HTN.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:78 |
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| Enthalten in: |
Acta cardiologica - 78(2023), 5 vom: 04. Juli, Seite 565-573 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Humbert, Xavier [VerfasserIn] |
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| Links: |
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| Themen: |
268B43MJ25 |
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| Anmerkungen: |
Date Completed 18.07.2023 Date Revised 18.07.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1080/00015385.2022.2088170 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM342484729 |
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| 100 | 1 | |a Humbert, Xavier |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Relationship between lifestyle factors and hypertension |b a cross-sectional analysis from the Gubbio study |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: Hypertension (HTN) is a well-established and a major risk factor for cardiovascular disease. Lifestyle behaviours for its prevention and control are recommended within worldwide guidelines. Their relationship with HTN need more investigations | ||
| 520 | |a AIM: We aimed to investigate the associations between lifestyle, anthropometric and biological measurements and BP in the Gubbio residential study | ||
| 520 | |a METHODS: Cross-sectional analyses were performed using data from Gubbio study. Information concerning lifestyle factors were collected using self-reported questionnaire and were further completed with a baseline clinical examination and blood exams. Three BP measurements were performed following a standard protocol. Age-adjusted and multivariable logistic regressions were used to examine the relationships between lifestyle parameters and HTN separately for each sex. We used heterogeneity test to observe sex differences | ||
| 520 | |a RESULTS: There were 3,183 persons included (48% men, 43 ± 17 years old). Mean systolic BP (SBP) was 119 ± 16 mmHg and 10.6% were hypertensives. Age [OR: 129.70 (95%CI: 18.57-905.79) in women and OR: 8.37 (95%CI: 4.01-17.48) (p < 0.0001) in men] and BMI [OR: 2.14 (95%CI: 1.32-3.46) (p = 0.006) in women and OR: 1.81 (95%CI: 1.05-3.12), p = 0.03 in men], were positively associated with SBP in both sexes. Serum uric acid [OR: 3.86 (95%CI: 2.03-7.26), p = 0.04] was positively associated with HTN in women while fasting blood glucose [OR: 3.04 (95%CI: 1.55-5.97), p < 0.001] were associated to HTN only in men | ||
| 520 | |a DISCUSSION: In addition to age, BMI is associated with HTN in both sexes while sex differences were observed in the associations between serum uric acid, fasting blood glucose and HTN | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Blood pressure | |
| 650 | 4 | |a hypertension | |
| 650 | 4 | |a prevention | |
| 650 | 4 | |a sex difference | |
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| 650 | 7 | |a Blood Glucose |2 NLM | |
| 700 | 1 | |a Licaj, Idlir |e verfasserin |4 aut | |
| 700 | 1 | |a Fedrizzi, Sophie |e verfasserin |4 aut | |
| 700 | 1 | |a Alexandre, Joachim |e verfasserin |4 aut | |
| 700 | 1 | |a Menotti, Alessandro |e verfasserin |4 aut | |
| 700 | 1 | |a Manrique, Alain |e verfasserin |4 aut | |
| 700 | 1 | |a Allouche, Stéphane |e verfasserin |4 aut | |
| 700 | 1 | |a Touzé, Emmanuel |e verfasserin |4 aut | |
| 700 | 1 | |a Terradura-Vagnarelli, Oscar |e verfasserin |4 aut | |
| 700 | 1 | |a Puddu, Paolo E |e verfasserin |4 aut | |
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