Comparing the Sensitivity and Specificity of Lung CT-scan with RT-PCR for Diagnosis of COVID-19
Copyright© Bentham Science Publishers; For any queries, please email at epubbenthamscience.net..
BACKGROUND: The lung is one of the major organs affected by the SARS-CoV-2 virus. Lung CT scan and RT-PCR are the most valuable diagnostic methods in the early diagnosis and management of COVID-19. Due to the possible inconsistency of the false-negative results for the RT-PCR test, in our study, we aimed to evaluate the sensitivity and specificity of lung CT-scan as an accurate diagnostic method of COVID-19.
METHODS: In this cross-sectional study, patients suspected of COVID-19 and referred to Shahid Beheshti Hospital in Qom city from February 26 to April 13, 2020, were enrolled. For a definitive diagnosis of COVID-19, chest CT scan and RT-PCR testing was performed for 644 patients, and both sensitivity and specificity of lung CT scan were evaluated.
RESULTS: According to the findings, and comparing to the RT-PCR test as the gold standard, sensitivity, specificity as well as, positive predictive and negative predictive values of lung CT-scan were found as follow; 94.47% (95% CI: 90.73 - 97.02%), 24.71% (95% CI: 20.70 - 29.07%), 40.73% (95% CI: 36.58 - 44.99%), 89.08% (95% CI: 82.4 - 94.05%), respectively.
CONCLUSION: According to the findings, the lung CT scan has a better diagnostic value than RTPCR in symptomatic patients who were referred to the hospital for COVID-19 diagnosis. Performing lung CT-scan in patients with negative RT-PCR tests should be assessed.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2023 |
|---|---|
| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:19 |
|---|---|
| Enthalten in: |
Current medical imaging - 19(2023), 4 vom: 01., Seite 327-332 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Asghari, Akram [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
COVID-19 |
|---|
| Anmerkungen: |
Date Completed 12.04.2023 Date Revised 13.04.2023 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.2174/1573405618666220620141012 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM342476297 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM342476297 | ||
| 003 | DE-627 | ||
| 005 | 20231226014213.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.2174/1573405618666220620141012 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1141.xml |
| 035 | |a (DE-627)NLM342476297 | ||
| 035 | |a (NLM)35726406 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Asghari, Akram |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Comparing the Sensitivity and Specificity of Lung CT-scan with RT-PCR for Diagnosis of COVID-19 |
| 264 | 1 | |c 2023 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 12.04.2023 | ||
| 500 | |a Date Revised 13.04.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright© Bentham Science Publishers; For any queries, please email at epubbenthamscience.net. | ||
| 520 | |a BACKGROUND: The lung is one of the major organs affected by the SARS-CoV-2 virus. Lung CT scan and RT-PCR are the most valuable diagnostic methods in the early diagnosis and management of COVID-19. Due to the possible inconsistency of the false-negative results for the RT-PCR test, in our study, we aimed to evaluate the sensitivity and specificity of lung CT-scan as an accurate diagnostic method of COVID-19 | ||
| 520 | |a METHODS: In this cross-sectional study, patients suspected of COVID-19 and referred to Shahid Beheshti Hospital in Qom city from February 26 to April 13, 2020, were enrolled. For a definitive diagnosis of COVID-19, chest CT scan and RT-PCR testing was performed for 644 patients, and both sensitivity and specificity of lung CT scan were evaluated | ||
| 520 | |a RESULTS: According to the findings, and comparing to the RT-PCR test as the gold standard, sensitivity, specificity as well as, positive predictive and negative predictive values of lung CT-scan were found as follow; 94.47% (95% CI: 90.73 - 97.02%), 24.71% (95% CI: 20.70 - 29.07%), 40.73% (95% CI: 36.58 - 44.99%), 89.08% (95% CI: 82.4 - 94.05%), respectively | ||
| 520 | |a CONCLUSION: According to the findings, the lung CT scan has a better diagnostic value than RTPCR in symptomatic patients who were referred to the hospital for COVID-19 diagnosis. Performing lung CT-scan in patients with negative RT-PCR tests should be assessed | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a CT scan | |
| 650 | 4 | |a RT-PCR | |
| 650 | 4 | |a diagnosis | |
| 650 | 4 | |a sensitivity | |
| 650 | 4 | |a specificity | |
| 700 | 1 | |a Adeli, Seyed-Hasan |e verfasserin |4 aut | |
| 700 | 1 | |a Parham, Mahmoud |e verfasserin |4 aut | |
| 700 | 1 | |a Bagherzade, Mohammad |e verfasserin |4 aut | |
| 700 | 1 | |a Ahmadpour, Sajjad |e verfasserin |4 aut | |
| 700 | 1 | |a Shajari, Rasoul |e verfasserin |4 aut | |
| 700 | 1 | |a Tabarrai, Reihane |e verfasserin |4 aut | |
| 700 | 1 | |a Shakeri, Masoumeh |e verfasserin |4 aut | |
| 700 | 1 | |a Habibi, Mohammad Amin |e verfasserin |4 aut | |
| 700 | 1 | |a Jabbari, Amir |e verfasserin |4 aut | |
| 700 | 1 | |a Jafari, Saeede |e verfasserin |4 aut | |
| 700 | 1 | |a Razavinia, Fatemesadat |e verfasserin |4 aut | |
| 700 | 1 | |a Foroghi Ghomi, Seyed Yaser |e verfasserin |4 aut | |
| 700 | 1 | |a Ebrazeh, Ali |e verfasserin |4 aut | |
| 700 | 1 | |a Vafaeimanesh, Jamshid |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Current medical imaging |d 2020 |g 19(2023), 4 vom: 01., Seite 327-332 |w (DE-627)NLM306935120 |x 1573-4056 |7 nnns |
| 773 | 1 | 8 | |g volume:19 |g year:2023 |g number:4 |g day:01 |g pages:327-332 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.2174/1573405618666220620141012 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 19 |j 2023 |e 4 |b 01 |h 327-332 | ||