Risk of Postoperative Thromboembolism in Men Undergoing Urological Prosthetic Surgery : An Assessment of 21,413 Men
PURPOSE: We assessed venous thromboembolism (VTE) and associated risk factors following artificial urinary sphincter (AUS) and inflatable penile prosthesis (IPP) surgery.
MATERIALS AND METHODS: Using IBM® MarketScan, a commercial claims database, patients undergoing AUS and IPP surgery were identified using CPT® and ICD (International Classification of Diseases)-10 procedure codes between 2008 and 2017. ICD-9 and -10 codes were used to identify health care visits associated with lower extremity deep vein thrombosis (DVT) and pulmonary embolism (PE) within 90 days of surgery. Covariates were assessed using a multivariable model to determine association with outcome of DVT and/or PE.
RESULTS: A total of 21,413 men underwent AUS (4,870) or IPP (16,543) surgery between 2008 and 2017 with a median age of 62 years and 68 years, respectively. DVT and PE events following AUS and IPP surgery occurred in 1.54% and 1.04%, respectively. A history of varicose veins (HR 2.76; 95% CI 1.11-6.79), prior history of DVT (HR 13.65; 95% CI 7.4-25.19), or PE (HR 7.65; 95% CI 4.01-14.6) in those undergoing AUS surgery was highly associated with development of postoperative VTE. Likewise, prior history of DVT (HR 12.6; 95% CI 7.99-19.93) and PE (HR 8.9; 95% CI 5.6-14.13) was strongly associated with a VTE event following IPP surgery.
CONCLUSIONS: In a large cohort of men undergoing AUS and IPP surgery, 1.54% and 1.04% of men experienced a VTE event within 90 days of surgery, respectively. Prior history of varicose veins, DVT, and PE was associated with an increased likelihood of developing a postoperative DVT or PE.
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:208 |
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| Enthalten in: |
The Journal of urology - 208(2022), 4 vom: 05. Okt., Seite 878-885 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Hebert, Kevin J [VerfasserIn] |
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| Links: |
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| Themen: |
Anticoagulants |
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| Anmerkungen: |
Date Completed 13.09.2022 Date Revised 14.09.2022 published: Print-Electronic CommentIn: J Urol. 2022 Oct;208(4):884-885. - PMID 35881708 Citation Status MEDLINE |
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| doi: |
10.1097/JU.0000000000002801 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM34208528X |
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| 041 | |a eng | ||
| 100 | 1 | |a Hebert, Kevin J |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Risk of Postoperative Thromboembolism in Men Undergoing Urological Prosthetic Surgery |b An Assessment of 21,413 Men |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 13.09.2022 | ||
| 500 | |a Date Revised 14.09.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a CommentIn: J Urol. 2022 Oct;208(4):884-885. - PMID 35881708 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a PURPOSE: We assessed venous thromboembolism (VTE) and associated risk factors following artificial urinary sphincter (AUS) and inflatable penile prosthesis (IPP) surgery | ||
| 520 | |a MATERIALS AND METHODS: Using IBM® MarketScan, a commercial claims database, patients undergoing AUS and IPP surgery were identified using CPT® and ICD (International Classification of Diseases)-10 procedure codes between 2008 and 2017. ICD-9 and -10 codes were used to identify health care visits associated with lower extremity deep vein thrombosis (DVT) and pulmonary embolism (PE) within 90 days of surgery. Covariates were assessed using a multivariable model to determine association with outcome of DVT and/or PE | ||
| 520 | |a RESULTS: A total of 21,413 men underwent AUS (4,870) or IPP (16,543) surgery between 2008 and 2017 with a median age of 62 years and 68 years, respectively. DVT and PE events following AUS and IPP surgery occurred in 1.54% and 1.04%, respectively. A history of varicose veins (HR 2.76; 95% CI 1.11-6.79), prior history of DVT (HR 13.65; 95% CI 7.4-25.19), or PE (HR 7.65; 95% CI 4.01-14.6) in those undergoing AUS surgery was highly associated with development of postoperative VTE. Likewise, prior history of DVT (HR 12.6; 95% CI 7.99-19.93) and PE (HR 8.9; 95% CI 5.6-14.13) was strongly associated with a VTE event following IPP surgery | ||
| 520 | |a CONCLUSIONS: In a large cohort of men undergoing AUS and IPP surgery, 1.54% and 1.04% of men experienced a VTE event within 90 days of surgery, respectively. Prior history of varicose veins, DVT, and PE was associated with an increased likelihood of developing a postoperative DVT or PE | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a heparin | |
| 650 | 4 | |a penile prosthesis | |
| 650 | 4 | |a pulmonary embolism | |
| 650 | 4 | |a urinary sphincter, artificial | |
| 650 | 4 | |a venous thromboembolism | |
| 650 | 7 | |a Anticoagulants |2 NLM | |
| 700 | 1 | |a Matta, Rano |e verfasserin |4 aut | |
| 700 | 1 | |a Horns, Joshua J |e verfasserin |4 aut | |
| 700 | 1 | |a Paudel, Niraj |e verfasserin |4 aut | |
| 700 | 1 | |a Das, Rupam |e verfasserin |4 aut | |
| 700 | 1 | |a Kohler, Tobias S |e verfasserin |4 aut | |
| 700 | 1 | |a Pastuszak, Alexander W |e verfasserin |4 aut | |
| 700 | 1 | |a McCormick, Benjamin J |e verfasserin |4 aut | |
| 700 | 1 | |a Hotaling, James M |e verfasserin |4 aut | |
| 700 | 1 | |a Myers, Jeremy B |e verfasserin |4 aut | |
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