A Recovery-Oriented Intervention for People With Psychosis : A Pilot Randomized Controlled Trial
OBJECTIVE: This pilot randomized controlled trial evaluated the effectiveness of critical time intervention-task shifting (CTI-TS) for people with psychosis in Santiago, Chile, and Rio de Janeiro. CTI-TS is a 9-month intervention involving peer support workers and is designed to maintain treatment effects up to 18 months.
METHODS: A total of 110 people with psychosis were recruited when they enrolled in community mental health clinics (Santiago, N=60; Rio de Janeiro, N=50). Participants within each city were randomly assigned to either CTI-TS or usual care for 9 months. Primary outcomes were quality of life, measured with the World Health Organization Quality of Life Assessment-Brief Version (WHOQOL-BREF), and unmet needs, measured with the Camberwell Assessment of Need (CAN), at 18-month follow-up. Results were analyzed according to intention-to-treat guidelines. Generalized estimating equations, with observations clustered within cities, and multiple imputation for missing data were used.
RESULTS: At 18 months, both groups showed improved primary outcomes. In both unadjusted and fully adjusted analyses, no significant differences between CTI-TS and usual care (WHOQOL-BREF question on quality of life and CAN mean number of unmet needs) were found.
CONCLUSIONS: Three factors might explain the lack of difference between CTI-TS and usual care: first-contact enrollment precluded rapport prior to randomization, a minority of patients were uncomfortable with peers being on the treatment team, and primary outcome measures may not have been sensitive enough to capture the effects of a recovery-oriented intervention. The results have implications for the design of transitional services for people with psychosis, especially in Latin America.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:73 |
|---|---|
| Enthalten in: |
Psychiatric services (Washington, D.C.) - 73(2022), 11 vom: 01. Nov., Seite 1225-1231 |
| Sprache: |
Englisch |
|---|
| Links: |
|---|
| Themen: |
Community mental health centers |
|---|
| Anmerkungen: |
Date Completed 02.11.2022 Date Revised 09.11.2022 published: Print-Electronic ClinicalTrials.gov: NCT01995864 Citation Status MEDLINE |
|---|
| doi: |
10.1176/appi.ps.202000843 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM341998435 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM341998435 | ||
| 003 | DE-627 | ||
| 005 | 20231226013048.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1176/appi.ps.202000843 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1139.xml |
| 035 | |a (DE-627)NLM341998435 | ||
| 035 | |a (NLM)35678081 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Mascayano, Franco |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A Recovery-Oriented Intervention for People With Psychosis |b A Pilot Randomized Controlled Trial |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 02.11.2022 | ||
| 500 | |a Date Revised 09.11.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a ClinicalTrials.gov: NCT01995864 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a OBJECTIVE: This pilot randomized controlled trial evaluated the effectiveness of critical time intervention-task shifting (CTI-TS) for people with psychosis in Santiago, Chile, and Rio de Janeiro. CTI-TS is a 9-month intervention involving peer support workers and is designed to maintain treatment effects up to 18 months | ||
| 520 | |a METHODS: A total of 110 people with psychosis were recruited when they enrolled in community mental health clinics (Santiago, N=60; Rio de Janeiro, N=50). Participants within each city were randomly assigned to either CTI-TS or usual care for 9 months. Primary outcomes were quality of life, measured with the World Health Organization Quality of Life Assessment-Brief Version (WHOQOL-BREF), and unmet needs, measured with the Camberwell Assessment of Need (CAN), at 18-month follow-up. Results were analyzed according to intention-to-treat guidelines. Generalized estimating equations, with observations clustered within cities, and multiple imputation for missing data were used | ||
| 520 | |a RESULTS: At 18 months, both groups showed improved primary outcomes. In both unadjusted and fully adjusted analyses, no significant differences between CTI-TS and usual care (WHOQOL-BREF question on quality of life and CAN mean number of unmet needs) were found | ||
| 520 | |a CONCLUSIONS: Three factors might explain the lack of difference between CTI-TS and usual care: first-contact enrollment precluded rapport prior to randomization, a minority of patients were uncomfortable with peers being on the treatment team, and primary outcome measures may not have been sensitive enough to capture the effects of a recovery-oriented intervention. The results have implications for the design of transitional services for people with psychosis, especially in Latin America | ||
| 650 | 4 | |a Randomized Controlled Trial | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, N.I.H., Extramural | |
| 650 | 4 | |a Community mental health centers | |
| 650 | 4 | |a Community mental health services | |
| 650 | 4 | |a Latin America | |
| 650 | 4 | |a Peers | |
| 650 | 4 | |a Pilot RCT | |
| 650 | 4 | |a Psychoses | |
| 700 | 1 | |a Alvarado, Ruben |e verfasserin |4 aut | |
| 700 | 1 | |a Andrews, Howard F |e verfasserin |4 aut | |
| 700 | 1 | |a Baumgartner, Joy N |e verfasserin |4 aut | |
| 700 | 1 | |a Burrone, Maria Soledad |e verfasserin |4 aut | |
| 700 | 1 | |a Cintra, Jacqueline |e verfasserin |4 aut | |
| 700 | 1 | |a Conover, Sarah |e verfasserin |4 aut | |
| 700 | 1 | |a Dahl, Catarina M |e verfasserin |4 aut | |
| 700 | 1 | |a Fader, Kim M |e verfasserin |4 aut | |
| 700 | 1 | |a Gorroochurn, Prakash |e verfasserin |4 aut | |
| 700 | 1 | |a Galea, Sandro |e verfasserin |4 aut | |
| 700 | 1 | |a Jorquera, Maria J |e verfasserin |4 aut | |
| 700 | 1 | |a Lovisi, Giovanni M |e verfasserin |4 aut | |
| 700 | 1 | |a Mitkiewicz de Souza, Flavia |e verfasserin |4 aut | |
| 700 | 1 | |a Pratt, Charissa |e verfasserin |4 aut | |
| 700 | 1 | |a Restrepo-Toro, Maria E |e verfasserin |4 aut | |
| 700 | 1 | |a Rojas, Graciela |e verfasserin |4 aut | |
| 700 | 1 | |a Rodrigues Sarução, Keli |e verfasserin |4 aut | |
| 700 | 1 | |a Rosenheck, Robert |e verfasserin |4 aut | |
| 700 | 1 | |a Schilling, Sara |e verfasserin |4 aut | |
| 700 | 1 | |a Shriver, Tom |e verfasserin |4 aut | |
| 700 | 1 | |a Stastny, Peter |e verfasserin |4 aut | |
| 700 | 1 | |a Tapia, Eric |e verfasserin |4 aut | |
| 700 | 1 | |a Cavalcanti, Maria Tavares |e verfasserin |4 aut | |
| 700 | 1 | |a Valencia, Eliecer |e verfasserin |4 aut | |
| 700 | 1 | |a Yang, Lawrence H |e verfasserin |4 aut | |
| 700 | 1 | |a Restrepo Henao, Alexandra |e verfasserin |4 aut | |
| 700 | 1 | |a Martínez-Alés, Gonzalo |e verfasserin |4 aut | |
| 700 | 1 | |a Romero Pardo, Victor |e verfasserin |4 aut | |
| 700 | 1 | |a Gomez Alemany, Teresa |e verfasserin |4 aut | |
| 700 | 1 | |a Susser, Ezra |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Psychiatric services (Washington, D.C.) |d 1998 |g 73(2022), 11 vom: 01. Nov., Seite 1225-1231 |w (DE-627)NLM075107546 |x 1557-9700 |7 nnns |
| 773 | 1 | 8 | |g volume:73 |g year:2022 |g number:11 |g day:01 |g month:11 |g pages:1225-1231 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1176/appi.ps.202000843 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 73 |j 2022 |e 11 |b 01 |c 11 |h 1225-1231 | ||