The impact of eustachian tube function on intra-tympanic steroid administration
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature..
OBJECTIVES: This study investigated the impact of eustachian tube (ET) function (ETF) on therapeutic success on candidates for intra-tympanic administration of steroids (ITAoS), due to idiopathic sudden sensorineural hearing loss (ISSNHL).
METHODS: Medical chart review in two university-affiliated medical centers was performed. Included were consecutive adult patients diagnosed with unilateral ISSNHL between 2012 and 2019 who were treated with ITAoS due to incomplete or no recovery following systemic steroidal therapy. ETF was assessed by means tympanometry, before the initiation of ITAoS. The cohort was divided into an ET dysfunction group (ETD(+)) and a functioning ET group (control: ETD(-)). The audiologic response to treatment was recorded at the last follow-up.
RESULTS: A total of 64 suitable patients [median (interquartile, IQR) age 49 (38-63) years] were enrolled. The ETD(+) group included 20 patients and the remaining 44 patients served as controls. Demographic and clinical parameters were not significantly different between the two groups at presentation. Hearing thresholds were improved significantly better, at frequencies 250, 500, 1, 2, 4, and 8 kHz (p = 0.001-0.040) in the ETD(+) group.
CONCLUSION: ETD(+) is associated with better efficacy of ITAoS.
LEVEL OF EVIDENCE: 4:.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:280 |
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| Enthalten in: |
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 280(2023), 1 vom: 07. Jan., Seite 143-149 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Chavkin, Uri [VerfasserIn] |
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| Links: |
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| Themen: |
Eustachian tube dysfunction |
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| Anmerkungen: |
Date Completed 06.01.2023 Date Revised 11.01.2023 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1007/s00405-022-07475-8 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM341927074 |
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| 520 | |a © 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. | ||
| 520 | |a OBJECTIVES: This study investigated the impact of eustachian tube (ET) function (ETF) on therapeutic success on candidates for intra-tympanic administration of steroids (ITAoS), due to idiopathic sudden sensorineural hearing loss (ISSNHL) | ||
| 520 | |a METHODS: Medical chart review in two university-affiliated medical centers was performed. Included were consecutive adult patients diagnosed with unilateral ISSNHL between 2012 and 2019 who were treated with ITAoS due to incomplete or no recovery following systemic steroidal therapy. ETF was assessed by means tympanometry, before the initiation of ITAoS. The cohort was divided into an ET dysfunction group (ETD(+)) and a functioning ET group (control: ETD(-)). The audiologic response to treatment was recorded at the last follow-up | ||
| 520 | |a RESULTS: A total of 64 suitable patients [median (interquartile, IQR) age 49 (38-63) years] were enrolled. The ETD(+) group included 20 patients and the remaining 44 patients served as controls. Demographic and clinical parameters were not significantly different between the two groups at presentation. Hearing thresholds were improved significantly better, at frequencies 250, 500, 1, 2, 4, and 8 kHz (p = 0.001-0.040) in the ETD(+) group | ||
| 520 | |a CONCLUSION: ETD(+) is associated with better efficacy of ITAoS | ||
| 520 | |a LEVEL OF EVIDENCE: 4: | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Eustachian tube dysfunction | |
| 650 | 4 | |a Idiopathic sudden sensorineural hearing loss | |
| 650 | 4 | |a Intratympanic steroids injection | |
| 650 | 4 | |a Sudden deafness | |
| 650 | 7 | |a Glucocorticoids |2 NLM | |
| 650 | 7 | |a Steroids |2 NLM | |
| 700 | 1 | |a Pitaro, Jacob |e verfasserin |4 aut | |
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| 700 | 1 | |a Handzel, Ophir |e verfasserin |4 aut | |
| 700 | 1 | |a Muhanna, Nidal |e verfasserin |4 aut | |
| 700 | 1 | |a Warshavsky, Anton |e verfasserin |4 aut | |
| 700 | 1 | |a Horowitz, Gilad |e verfasserin |4 aut | |
| 700 | 1 | |a Ungar, Omer J |e verfasserin |4 aut | |
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