The link between airway reflux and non-acid reflux in children : a review

Copyright © 2022 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier España, S.L.U. All rights reserved..

OBJECTIVE: Airway reflux, a member of extra-esophageal reflux, has been linked to countless respiratory pathologies amongst children. The advent of novel instrumentation has enabled the discovery of non-acid reflux which was postulated as the main culprit of airway reflux. The objective of this review is to outline the association between non-acid reflux and airway reflux in children.

METHODS: A comprehensive review of recent literature on non-acid reflux and airway reflux in children was conducted. Studies ranged from January 2010 till November 2021 were searched over a period of a month: December 2021.

RESULTS: A total of eleven studies were identified. All studies included in this review revealed a strong link between non-acid reflux and airway reflux in children. 6 of the included studies are prospective studies, 3 retrospective studies, 1 cross-section study, and type of study was not mentioned in 1 study. The most common reported respiratory manifestation of non-acid reflux in children was chronic cough (7 studies). Predominant non-acid reflux was noted in 4 studies. The total number of children in each study ranges from 21 to 150 patients. MII-pH study was carried out in all studies included as a diagnostic tool for reflux investigation.

CONCLUSION: Non-acid reflux is the culprit behind airway reflux as well as other myriads of extra-esophageal manifestations in children. Multicentre international studies with a standardized protocol could improve scientific knowledge in managing non-acid reflux in airway reflux amongst children.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:89

Enthalten in:

Brazilian journal of otorhinolaryngology - 89(2023), 2 vom: 06. März, Seite 329-338

Sprache:

Englisch

Beteiligte Personen:

Saniasiaya, Jeyasakthy [VerfasserIn]
Kulasegarah, Jeyanthi [VerfasserIn]

Links:

Volltext

Themen:

Airway reflux
Children
Gastroesophageal reflux
Journal Article
Laryngopharyngeal reflux
Non-acid reflux
Review

Anmerkungen:

Date Completed 31.03.2023

Date Revised 11.04.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.bjorl.2022.05.002

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM341816744