Diagnosis and management of pulmonary hypertension in infants with bronchopulmonary dysplasia
Copyright © 2022 Elsevier Ltd. All rights reserved..
Chronic pulmonary hypertension of infancy (cPHi) is a heterogeneous disease process that contributes to morbidity and mortality in preterm infants. cPHi is most commonly associated with chronic lung disease of prematurity and represents a unique phenotype of bronchopulmonary dysplasia. It is characterized by persistently elevated or newly rising pulmonary vascular resistance and pulmonary artery pressure beyond the first weeks of age. The high-pressure afterload on the right ventricle may or may not be tolerated, depending upon additional cardiovascular shunting and co-morbidities. A comprehensive clinical evaluation combined with advanced hemodynamic assessment by echocardiography and other cardiac imaging modalities help decipher the etiopathologies of disease, identify cardiopulmonary compromise earlier and guide individualized therapeutic intervention tailored by the phenotype. This review summarizes the underlying etiologies, risk factors for development, hemodynamic assessment, management, and follow-up of cPHi in preterm infants. We offer an algorithm for early detection of cPHi and outline research priorities.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:27 |
|---|---|
| Enthalten in: |
Seminars in fetal & neonatal medicine - 27(2022), 4 vom: 15. Aug., Seite 101351 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Levy, Philip T [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Bronchopulmonary dysplasia |
|---|
| Anmerkungen: |
Date Completed 13.09.2022 Date Revised 12.10.2022 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.siny.2022.101351 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM34163574X |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM34163574X | ||
| 003 | DE-627 | ||
| 005 | 20231226012233.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.siny.2022.101351 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1138.xml |
| 035 | |a (DE-627)NLM34163574X | ||
| 035 | |a (NLM)35641413 | ||
| 035 | |a (PII)S1744-165X(22)00030-0 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Levy, Philip T |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Diagnosis and management of pulmonary hypertension in infants with bronchopulmonary dysplasia |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 13.09.2022 | ||
| 500 | |a Date Revised 12.10.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2022 Elsevier Ltd. All rights reserved. | ||
| 520 | |a Chronic pulmonary hypertension of infancy (cPHi) is a heterogeneous disease process that contributes to morbidity and mortality in preterm infants. cPHi is most commonly associated with chronic lung disease of prematurity and represents a unique phenotype of bronchopulmonary dysplasia. It is characterized by persistently elevated or newly rising pulmonary vascular resistance and pulmonary artery pressure beyond the first weeks of age. The high-pressure afterload on the right ventricle may or may not be tolerated, depending upon additional cardiovascular shunting and co-morbidities. A comprehensive clinical evaluation combined with advanced hemodynamic assessment by echocardiography and other cardiac imaging modalities help decipher the etiopathologies of disease, identify cardiopulmonary compromise earlier and guide individualized therapeutic intervention tailored by the phenotype. This review summarizes the underlying etiologies, risk factors for development, hemodynamic assessment, management, and follow-up of cPHi in preterm infants. We offer an algorithm for early detection of cPHi and outline research priorities | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Bronchopulmonary dysplasia | |
| 650 | 4 | |a Chronic pulmonary hypertension of infancy | |
| 650 | 4 | |a Echocardiography | |
| 650 | 4 | |a Prematurity | |
| 650 | 4 | |a Pulmonary vascular disease | |
| 650 | 4 | |a Screening | |
| 700 | 1 | |a Levin, Jonathan |e verfasserin |4 aut | |
| 700 | 1 | |a Leeman, Kristen T |e verfasserin |4 aut | |
| 700 | 1 | |a Mullen, Mary P |e verfasserin |4 aut | |
| 700 | 1 | |a Hansmann, Georg |e verfasserin |4 aut | |
| 700 | 1 | |a Kourembanas, Stella |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Seminars in fetal & neonatal medicine |d 2004 |g 27(2022), 4 vom: 15. Aug., Seite 101351 |w (DE-627)NLM15349798X |x 1878-0946 |7 nnns |
| 773 | 1 | 8 | |g volume:27 |g year:2022 |g number:4 |g day:15 |g month:08 |g pages:101351 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.siny.2022.101351 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 27 |j 2022 |e 4 |b 15 |c 08 |h 101351 | ||