Weight excess association with severity in children and adolescents with COVID-19 : A systematic review

Copyright © 2022 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved..

BACKGROUND & AIMS: Concomitantly to the coronavirus disease 2019 (COVID-19), in the child population there was already another pandemic wave in progress: childhood obesity. Numerous studies in adults have been carried out and describe obesity as an independent risk and prognostic factor for the severity of COVID-19. This study aims to systematically review the literature on the relation between weight excess and the severity of COVID-19 in children and adolescents.

METHODS: This systematic review was developed following the PRISMA standards (Preferred Reporting Items for Systematic Review and Meta-Analysis). The literature search was performed in September 2020, in the following databases: MEDLINE (via PubMed), Embase, Scopus, The Cochrane Library (Cochrane Database of Systematic Reviews and Cochrane Central Register of Controlled Trials (CENTRAL)), Web of Science, BVS/LILACS and SciELO. Registration on the PROSPERO platform (International Prospective Registry of Systematic Reviews) can be found under the registration number: CRD42021230686.

RESULTS: Of the 667 selected articles, 11 were included according to all agreed criteria, most of them being unicentric and American. In assessing the risk of bias and quality, following the criteria of the Newcastle-Ottawa Scale, eight studies achieved scores higher than 7. Only 5 studies sought to assess obesity and its relation with worse outcomes (such as need for pediatric intensive care unit (PICU), mechanical ventilation (MV), tracheostomy, hospital readmission and mortality), and out of these, only one article demonstrated this comorbidity as a prognostic factor for worse evolution of the COVID picture.

CONCLUSIONS: Few studies in the literature seek to assess excess weight and its relation with worse outcomes of COVID-19 in children and adolescents. Taking into account that there is already scientific evidence on this subject in adult patients, it is necessary to carry out more research in the pediatric age group.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:49

Enthalten in:

Clinical nutrition ESPEN - 49(2022) vom: 27. Juni, Seite 114-120

Sprache:

Englisch

Beteiligte Personen:

Oliveira da Silva Kist, Mayara Luíza [VerfasserIn]
Hanzen Andrades, Gabriela Rupp [VerfasserIn]
Drumond Costa, Caroline Abud [VerfasserIn]
Crestani, Francielly [VerfasserIn]
Ramos Garcia, Pedro Celiny [VerfasserIn]

Links:

Volltext

Themen:

COVID-19
Child obesity
Corona virus
Journal Article
Overweight
Pediatric intensive care unit
Research Support, Non-U.S. Gov't
Systematic Review

Anmerkungen:

Date Completed 31.05.2022

Date Revised 11.01.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.clnesp.2022.04.005

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM341461148