B cell depletion therapy using rituximab to induce long-term remission of recalcitrant skin lesions of subacute cutaneous lupus erythematosus

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A woman in her 20s presented with chilblains for 2 years and recent-onset photodistributed psoriasiform plaques. She did not have persistent good improvement despite treatment with 1 mg/kg oral prednisolone, along with successive trials with many steroid-sparing adjuvants in adequate dosage and duration, including hydroxychloroquine, methotrexate and cyclosporine, in the following 6 months. The patient had an excellent improvement and went into remission with two doses of injection rituximab, 1 g each, at a 2-week interval. The remission was maintained during the 14-month follow-up.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:15

Enthalten in:

BMJ case reports - 15(2022), 5 vom: 27. Mai

Sprache:

Englisch

Beteiligte Personen:

Mehta, Nikhil [VerfasserIn]
Baskaran, Narayanan [VerfasserIn]
Arava, Sudheer [VerfasserIn]
Gupta, Somesh [VerfasserIn]

Links:

Volltext

Themen:

4F4X42SYQ6
4QWG6N8QKH
83HN0GTJ6D
Case Reports
Cyclosporine
Dermatology
Hydroxychloroquine
Journal Article
Rituximab
Skin

Anmerkungen:

Date Completed 31.05.2022

Date Revised 16.07.2022

published: Electronic

Citation Status MEDLINE

doi:

10.1136/bcr-2021-248476

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM341459666