Retinal vein occlusion in patients under 50 years. Analysis of vascular risk factors, thrombophilia, carotid ultrasound findings and uncommon aetiologies
Copyright © 2022 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved..
INTRODUTION: Retinal vein occlusion (RVO) has been related to vascular risk factors and thrombophilia.
METHODS: This is a prospective cohort study of all patients diagnosed with RVO and referred to an Internal Medicine clinic of a tertiary teaching hospital during a 10-year period. Clinical, laboratory and supra-aortic trunks ultrasound variables were analysed and compared according to age.
RESULTS: Some 309 patients diagnosed with RVO were included, 25 of them younger than 50 years. The prevalence of high blood pressure, dyslipidaemia, diabetes mellitus, hyperhomocysteinemia, and carotid plaque was significantly higher in patients >50 years than in those below. However, the prevalence of inherited thrombophilia was higher in the younger group (32.0% vs 11.4%; p = 0.005). Uncommon diseases related to RVO such as hepatitis C, thalassemia minor, Lyme disease, vasculitis, and periphlebitis were observed in young patients without vascular risk factors.
CONCLUSION: We suggest performing a genetic thrombophilia study in RVO patients younger than 50 years, while an exhaustive control of vascular risk factors is always recommended in all RVO patients. Moreover, we suggest bearing in mind uncommon diseases related to RVO, especially in young patients without vascular risk factors.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:97 |
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| Enthalten in: |
Archivos de la Sociedad Espanola de Oftalmologia - 97(2022), 8 vom: 23. Aug., Seite 443-449 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Sanlés González, I [VerfasserIn] |
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| Links: |
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| Themen: |
Factores de riesgo vascular |
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| Anmerkungen: |
Date Completed 03.08.2022 Date Revised 03.08.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.oftale.2021.12.002 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM341409642 |
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| 245 | 1 | 0 | |a Retinal vein occlusion in patients under 50 years. Analysis of vascular risk factors, thrombophilia, carotid ultrasound findings and uncommon aetiologies |
| 264 | 1 | |c 2022 | |
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| 500 | |a Date Completed 03.08.2022 | ||
| 500 | |a Date Revised 03.08.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2022 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved. | ||
| 520 | |a INTRODUTION: Retinal vein occlusion (RVO) has been related to vascular risk factors and thrombophilia | ||
| 520 | |a METHODS: This is a prospective cohort study of all patients diagnosed with RVO and referred to an Internal Medicine clinic of a tertiary teaching hospital during a 10-year period. Clinical, laboratory and supra-aortic trunks ultrasound variables were analysed and compared according to age | ||
| 520 | |a RESULTS: Some 309 patients diagnosed with RVO were included, 25 of them younger than 50 years. The prevalence of high blood pressure, dyslipidaemia, diabetes mellitus, hyperhomocysteinemia, and carotid plaque was significantly higher in patients >50 years than in those below. However, the prevalence of inherited thrombophilia was higher in the younger group (32.0% vs 11.4%; p = 0.005). Uncommon diseases related to RVO such as hepatitis C, thalassemia minor, Lyme disease, vasculitis, and periphlebitis were observed in young patients without vascular risk factors | ||
| 520 | |a CONCLUSION: We suggest performing a genetic thrombophilia study in RVO patients younger than 50 years, while an exhaustive control of vascular risk factors is always recommended in all RVO patients. Moreover, we suggest bearing in mind uncommon diseases related to RVO, especially in young patients without vascular risk factors | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Factores de riesgo vascular | |
| 650 | 4 | |a Hiperhomocisteinemia | |
| 650 | 4 | |a Hyperhomocysteinemia | |
| 650 | 4 | |a Oclusión venosa retiniana | |
| 650 | 4 | |a Retinal vein occlusion | |
| 650 | 4 | |a Thrombophilia | |
| 650 | 4 | |a Trombofilia | |
| 650 | 4 | |a Vascular risk factors | |
| 700 | 1 | |a Napal Lecumberri, J J |e verfasserin |4 aut | |
| 700 | 1 | |a Pérez-Montes, R |e verfasserin |4 aut | |
| 700 | 1 | |a Cerveró Varona, A |e verfasserin |4 aut | |
| 700 | 1 | |a Casado Rojo, A |e verfasserin |4 aut | |
| 700 | 1 | |a Hernández Hernández, J L |e verfasserin |4 aut | |
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