Novel and Innovative Approach of Nanotechnology with their Applications in the Management of Infectious Disease, Tuberculosis : An Overview

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Tuberculosis (TB) is considered a significant health problem caused by Mycobacterium tuberculosis. It is one of the second-deadly infectious diseases right after AIDS. Several factors such as poor patient compliance, high dose intake, low drug bioavailability and prolonged treatment of disease are responsible for the prevalence of multi-drug resistance tuberculosis and extensively drug-resistant tuberculosis cases. Therefore, developing such drug-resistant bacterial strains has created a robust and efficient system that can improve the therapeutic effectiveness of anti-tubercular drugs. This review manuscript highlights the therapeutic outcomes of a nanotechnology-based drug delivery system in treating TB. Various novel nanoformulations for anti-mycobacterial drugs have been explored. Such novel approaches would have shown several advantages such as sustained/controlled drug release, reduced dose frequency, and resolved poor patient compliance over many free anti-tubercular drugs. This framework will provide valuable information on various nanoparticle-based technology employed in treating TB infectious disease. Patent data were searched in google patent and nanoformulations outcomes for TB management improves health of patients.

Medienart:

E-Artikel

Erscheinungsjahr:

2024

Erschienen:

2024

Enthalten in:

Zur Gesamtaufnahme - volume:18

Enthalten in:

Recent patents on nanotechnology - 18(2024), 2 vom: 08., Seite 140-163

Sprache:

Englisch

Beteiligte Personen:

Singh, Sonia [VerfasserIn]
Ahuja, Ashima [VerfasserIn]

Links:

Volltext

Themen:

Antitubercular Agents
Controlled release
Journal Article
Mycobacterium tuberculosis
Nanoparticles.
Nanotechnology
Review
Sustained-release
Tuberculosis

Anmerkungen:

Date Completed 11.01.2024

Date Revised 26.04.2024

published: Print

Citation Status MEDLINE

doi:

10.2174/1872210516666220523122724

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM341390461