Potential Biological Roles of Exosomal Long Non-Coding RNAs in Gastrointestinal Cancer
Copyright © 2022 Kang, Jiang, Ouyang, Wu, Fu, Liu, Li, Tian, Cao, Wang and He..
Exosomes, a type of extracellular vesicles (EVs), are secreted by almost all cells and contain many cellular constituents, such as nucleic acids, lipids, and metabolites. In addition, they play a crucial role in intercellular communication and have been proved to be involved in the development and treatment of gastrointestinal cancer. It has been confirmed that long non-coding RNAs (lncRNAs) exert a range of biological functions, such as cell metastasis, tumorigenesis, and therapeutic responses. This review mainly focused on the emerging roles and underlying molecular mechanisms of exosome-derived lncRNAs in gastrointestinal cancer in recent years. The biological roles of exosomal lncRNAs in the pathogenesis and therapeutic responses of gastrointestinal cancers were also investigated.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:10 |
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| Enthalten in: |
Frontiers in cell and developmental biology - 10(2022) vom: 26., Seite 886191 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Kang, Fanhua [VerfasserIn] |
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| Links: |
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| Themen: |
Exosome |
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| Anmerkungen: |
Date Revised 16.07.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.3389/fcell.2022.886191 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM341251720 |
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| 520 | |a Copyright © 2022 Kang, Jiang, Ouyang, Wu, Fu, Liu, Li, Tian, Cao, Wang and He. | ||
| 520 | |a Exosomes, a type of extracellular vesicles (EVs), are secreted by almost all cells and contain many cellular constituents, such as nucleic acids, lipids, and metabolites. In addition, they play a crucial role in intercellular communication and have been proved to be involved in the development and treatment of gastrointestinal cancer. It has been confirmed that long non-coding RNAs (lncRNAs) exert a range of biological functions, such as cell metastasis, tumorigenesis, and therapeutic responses. This review mainly focused on the emerging roles and underlying molecular mechanisms of exosome-derived lncRNAs in gastrointestinal cancer in recent years. The biological roles of exosomal lncRNAs in the pathogenesis and therapeutic responses of gastrointestinal cancers were also investigated | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a pathogenesis | |
| 650 | 4 | |a treatment | |
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| 700 | 1 | |a Ouyang, Lingzi |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Shangjun |e verfasserin |4 aut | |
| 700 | 1 | |a Fu, Chencheng |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Ying |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Zhilan |e verfasserin |4 aut | |
| 700 | 1 | |a Tian, Yu |e verfasserin |4 aut | |
| 700 | 1 | |a Cao, Xiaolan |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Xiaoping |e verfasserin |4 aut | |
| 700 | 1 | |a He, Qingchun |e verfasserin |4 aut | |
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