Nasal nitric oxide May not differentiate primary ciliary dyskinesia from certain primary immunodeficiencies
© 2022 Wiley Periodicals LLC..
The diagnosis of primary ciliary dyskinesia (PCD) is made through a combination of clinical features supported by a panel of diagnostic tests. Our cases highlight the similarities in the clinical presentation of patients with the specific immunodeficiency activated phosphatidylinositol 3-kinase delta syndrome 1 (or PIK3CD-related disorder) and PCD. We highlight the importance of repeating nasal nitric oxide testing when PCD has not been confirmed by genetic or ciliary electron micrograph analysis in the setting of an expanded suppurative lung disease differential that includes considerations for immunodeficiency as well as PCD.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2022 |
---|---|
Erschienen: |
2022 |
Enthalten in: |
Zur Gesamtaufnahme - volume:57 |
---|---|
Enthalten in: |
Pediatric pulmonology - 57(2022), 9 vom: 30. Sept., Seite 2269-2272 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Saunders, Jessica L [VerfasserIn] |
---|
Links: |
---|
Themen: |
31C4KY9ESH |
---|
Anmerkungen: |
Date Completed 23.08.2022 Date Revised 24.08.2022 published: Print-Electronic Citation Status MEDLINE |
---|
doi: |
10.1002/ppul.25989 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM341188174 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM341188174 | ||
003 | DE-627 | ||
005 | 20231226011214.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231226s2022 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1002/ppul.25989 |2 doi | |
028 | 5 | 2 | |a pubmed24n1137.xml |
035 | |a (DE-627)NLM341188174 | ||
035 | |a (NLM)35596239 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Saunders, Jessica L |e verfasserin |4 aut | |
245 | 1 | 0 | |a Nasal nitric oxide May not differentiate primary ciliary dyskinesia from certain primary immunodeficiencies |
264 | 1 | |c 2022 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 23.08.2022 | ||
500 | |a Date Revised 24.08.2022 | ||
500 | |a published: Print-Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a © 2022 Wiley Periodicals LLC. | ||
520 | |a The diagnosis of primary ciliary dyskinesia (PCD) is made through a combination of clinical features supported by a panel of diagnostic tests. Our cases highlight the similarities in the clinical presentation of patients with the specific immunodeficiency activated phosphatidylinositol 3-kinase delta syndrome 1 (or PIK3CD-related disorder) and PCD. We highlight the importance of repeating nasal nitric oxide testing when PCD has not been confirmed by genetic or ciliary electron micrograph analysis in the setting of an expanded suppurative lung disease differential that includes considerations for immunodeficiency as well as PCD | ||
650 | 4 | |a Letter | |
650 | 4 | |a nasal nitric oxide | |
650 | 4 | |a primary ciliary dyskinesia | |
650 | 4 | |a primary immunodeficiency | |
650 | 7 | |a Nitric Oxide |2 NLM | |
650 | 7 | |a 31C4KY9ESH |2 NLM | |
700 | 1 | |a O'Connor, Michael Glenn |e verfasserin |4 aut | |
700 | 1 | |a Machogu, Evans M |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Pediatric pulmonology |d 1993 |g 57(2022), 9 vom: 30. Sept., Seite 2269-2272 |w (DE-627)NLM012888230 |x 1099-0496 |7 nnns |
773 | 1 | 8 | |g volume:57 |g year:2022 |g number:9 |g day:30 |g month:09 |g pages:2269-2272 |
856 | 4 | 0 | |u http://dx.doi.org/10.1002/ppul.25989 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 57 |j 2022 |e 9 |b 30 |c 09 |h 2269-2272 |