Water-soluble AIE-active fluorescent organic nanoparticles for ratiometric detection of SO2 in the mitochondria of living cells
We report a water-soluble AIEgen (TYDL) to be self-assembled into fluorescent organic nanoparticles (TYDLs) for specific sensing of SO2 in living hepatoma cells. It is demonstrated that the TYDLs were suitable for ratiometrically detecting endogenous and exogenous SO2 in mitochondria with good selectivity, low detection limit (75 nM) and excellent photostability (>30 min). These findings imply the great potential applications of TYDLs for the diagnosis of SO2-related diseases in cell biology.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:58 |
|---|---|
| Enthalten in: |
Chemical communications (Cambridge, England) - 58(2022), 46 vom: 08. Juni, Seite 6618-6621 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Feng, Gai-Li [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
059QF0KO0R |
|---|
| Anmerkungen: |
Date Completed 09.06.2022 Date Revised 09.06.2022 published: Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1039/d2cc02168d |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM341067229 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM341067229 | ||
| 003 | DE-627 | ||
| 005 | 20231226010922.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1039/d2cc02168d |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1136.xml |
| 035 | |a (DE-627)NLM341067229 | ||
| 035 | |a (NLM)35583952 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Feng, Gai-Li |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Water-soluble AIE-active fluorescent organic nanoparticles for ratiometric detection of SO2 in the mitochondria of living cells |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 09.06.2022 | ||
| 500 | |a Date Revised 09.06.2022 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a We report a water-soluble AIEgen (TYDL) to be self-assembled into fluorescent organic nanoparticles (TYDLs) for specific sensing of SO2 in living hepatoma cells. It is demonstrated that the TYDLs were suitable for ratiometrically detecting endogenous and exogenous SO2 in mitochondria with good selectivity, low detection limit (75 nM) and excellent photostability (>30 min). These findings imply the great potential applications of TYDLs for the diagnosis of SO2-related diseases in cell biology | ||
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Fluorescent Dyes |2 NLM | |
| 650 | 7 | |a Water |2 NLM | |
| 650 | 7 | |a 059QF0KO0R |2 NLM | |
| 650 | 7 | |a Sulfur Dioxide |2 NLM | |
| 650 | 7 | |a 0UZA3422Q4 |2 NLM | |
| 700 | 1 | |a Liu, Yi-Chen |e verfasserin |4 aut | |
| 700 | 1 | |a Ji, Yan-Ming |e verfasserin |4 aut | |
| 700 | 1 | |a Zhou, Wei |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Xia-Fen |e verfasserin |4 aut | |
| 700 | 1 | |a Hou, Min |e verfasserin |4 aut | |
| 700 | 1 | |a Gao, Jie-Lei |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Yuan |e verfasserin |4 aut | |
| 700 | 1 | |a Xing, Guo-Wen |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Chemical communications (Cambridge, England) |d 1998 |g 58(2022), 46 vom: 08. Juni, Seite 6618-6621 |w (DE-627)NLM095512322 |x 1364-548X |7 nnns |
| 773 | 1 | 8 | |g volume:58 |g year:2022 |g number:46 |g day:08 |g month:06 |g pages:6618-6621 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1039/d2cc02168d |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 58 |j 2022 |e 46 |b 08 |c 06 |h 6618-6621 | ||