American Canine Hepatozoonosis Causes Multifocal Periosteal Proliferation on CT : A Case Report of 4 Dogs
Copyright © 2022 Coy, Evans, Lee, Dugat, Levine and Griffin..
American canine hepatozoonosis (ACH) represents an important but relatively uncommon differential diagnosis in a dog with fever, muscle wasting, profound leukocytosis, and/or musculoskeletal pain. Despite this, obtaining a definitive diagnosis can prove difficult. Peripheral blood smears and whole-blood polymerase chain reaction (PCR) rely on rare parasitemia, and the gold standard diagnostic test (skeletal muscle biopsy) is uncommonly pursued due to its invasive and costly nature. Demonstration of characteristic periosteal proliferative lesions aids diagnosis. The lesions typically involve the more proximal long bones of the appendicular skeleton. The periosteal proliferation is of currently unknown pathogenesis, but its distribution is characteristic of this disease with few differential diagnoses. This case series describes the findings on computed tomography (CT) in 4 dogs with PCR- or cytologically-confirmed Hepatozoon americanum. All dogs had multifocal, bilaterally asymmetric, irregularly marginated, non-destructive, non-articular, periosteal proliferative lesions. Recognition of this unusual CT finding and awareness of this disease could assist in the diagnosis and subsequent treatment of dogs with ACH and may offer an additional indication for CT in cases of fever, muscle wasting, and myalgia.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2022 |
---|---|
Erschienen: |
2022 |
Enthalten in: |
Zur Gesamtaufnahme - volume:9 |
---|---|
Enthalten in: |
Frontiers in veterinary science - 9(2022) vom: 10., Seite 872778 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Coy, Cambridge L [VerfasserIn] |
---|
Links: |
---|
Themen: |
Canis |
---|
Anmerkungen: |
Date Revised 19.05.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
---|
doi: |
10.3389/fvets.2022.872778 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM340962917 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM340962917 | ||
003 | DE-627 | ||
005 | 20231226010655.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231226s2022 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.3389/fvets.2022.872778 |2 doi | |
028 | 5 | 2 | |a pubmed24n1136.xml |
035 | |a (DE-627)NLM340962917 | ||
035 | |a (NLM)35573416 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Coy, Cambridge L |e verfasserin |4 aut | |
245 | 1 | 0 | |a American Canine Hepatozoonosis Causes Multifocal Periosteal Proliferation on CT |b A Case Report of 4 Dogs |
264 | 1 | |c 2022 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Revised 19.05.2022 | ||
500 | |a published: Electronic-eCollection | ||
500 | |a Citation Status PubMed-not-MEDLINE | ||
520 | |a Copyright © 2022 Coy, Evans, Lee, Dugat, Levine and Griffin. | ||
520 | |a American canine hepatozoonosis (ACH) represents an important but relatively uncommon differential diagnosis in a dog with fever, muscle wasting, profound leukocytosis, and/or musculoskeletal pain. Despite this, obtaining a definitive diagnosis can prove difficult. Peripheral blood smears and whole-blood polymerase chain reaction (PCR) rely on rare parasitemia, and the gold standard diagnostic test (skeletal muscle biopsy) is uncommonly pursued due to its invasive and costly nature. Demonstration of characteristic periosteal proliferative lesions aids diagnosis. The lesions typically involve the more proximal long bones of the appendicular skeleton. The periosteal proliferation is of currently unknown pathogenesis, but its distribution is characteristic of this disease with few differential diagnoses. This case series describes the findings on computed tomography (CT) in 4 dogs with PCR- or cytologically-confirmed Hepatozoon americanum. All dogs had multifocal, bilaterally asymmetric, irregularly marginated, non-destructive, non-articular, periosteal proliferative lesions. Recognition of this unusual CT finding and awareness of this disease could assist in the diagnosis and subsequent treatment of dogs with ACH and may offer an additional indication for CT in cases of fever, muscle wasting, and myalgia | ||
650 | 4 | |a Case Reports | |
650 | 4 | |a canis | |
650 | 4 | |a case report | |
650 | 4 | |a gulf coast | |
650 | 4 | |a neutrophilia | |
650 | 4 | |a periosteum | |
650 | 4 | |a pseudocortex | |
650 | 4 | |a tick | |
700 | 1 | |a Evans, Jeremy B |e verfasserin |4 aut | |
700 | 1 | |a Lee, Alison M |e verfasserin |4 aut | |
700 | 1 | |a Dugat, Danielle R |e verfasserin |4 aut | |
700 | 1 | |a Levine, Jonathan M |e verfasserin |4 aut | |
700 | 1 | |a Griffin, John F |c 4th |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Frontiers in veterinary science |d 2014 |g 9(2022) vom: 10., Seite 872778 |w (DE-627)NLM255535317 |x 2297-1769 |7 nnns |
773 | 1 | 8 | |g volume:9 |g year:2022 |g day:10 |g pages:872778 |
856 | 4 | 0 | |u http://dx.doi.org/10.3389/fvets.2022.872778 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 9 |j 2022 |b 10 |h 872778 |