Venovenous Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Anti-neutrophil Cytoplasmic Autoantibody-associated Vasculitis : Starting without Systemic Anticoagulation

Regarding extracorporeal membrane oxygenation (ECMO) support against hemorrhagic conditions, there seems to be a dilemma when deciding between maintaining the circuit patency by systemic anticoagulation and increasing the risk of bleeding. We herein report two cases of diffuse alveolar hemorrhage (DAH) caused by myeloperoxidase (MPO) anti-neutrophil cytoplasmic autoantibody-associated vasculitis (AAV) successfully treated with venovenous (VV)-ECMO support, both initially started without systemic anticoagulation. Under anticoagulation-free ECMO management, we should consider the shortcomings of frequent circuit exchange and hemorrhagic diathesis related to circuit-induced disseminated intravascular coagulation (DIC).

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:61

Enthalten in:

Internal medicine (Tokyo, Japan) - 61(2022), 23 vom: 01. Dez., Seite 3569-3573

Sprache:

Englisch

Beteiligte Personen:

Ohta, Soichi [VerfasserIn]
Matsuyoshi, Takeo [VerfasserIn]
Kaneko, Hitoshi [VerfasserIn]
Kosen, Daiyu [VerfasserIn]
Suzuki, Hiroaki [VerfasserIn]
Hamaguchi, Jun [VerfasserIn]
Sato, Yuichi [VerfasserIn]
Shimizu, Keiki [VerfasserIn]

Links:

Volltext

Themen:

Autoantibodies
Diffuse alveolar hemorrhage
Extracorporeal membrane oxygenation
Journal Article
Myeloperoxidase anti-neutrophil cytoplasmic autoantibody-associated vasculitis

Anmerkungen:

Date Completed 02.12.2022

Date Revised 06.01.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.2169/internalmedicine.9472-22

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM340928719