Importance of the neutrophil-lymphocyte ratio in its association with mortality in patients with COVID-19 : Experience in a health center in Argentina
BACKGROUND: COVID-19 rapidly progresses to acute respiratory failure and mortality. A pandemic needs an urgent requirement for low-cost and easy-access tools that assess the infection evolution. The neutrophil-lymphocyte ratio (NLR) is an inflammatory biomarker used in several diseases.
AIM: To estimate the association between NLR > 3 with mortality in hospitalized patients with COVID 19.
METHODS: NLR was analyzed in patients with COVID-19 seen at Hospital Fernandez between March and August 2020. Patients were grouped in those with NLR < 3 and those with NLR > 3. Clinical characteristics and mortality were analyzed and compared between groups. A multivariable regression model was used to estimate the association between NLR > 3 and mortality.
RESULTS: We included 711 patients with COVID-19. In a multivariable regression model, NLR > 3 associated with mortality (OR 3.8; 95% CI 1.05 to 13.7; p 0.04) adjusting by age, days of hospitalization, intensive care requirement, severe pneumonia, C-reactive protein levels, arterial hypertension, and comorbidities.
CONCLUSION: NLR was associated with mortality, and it is an accessible and easy tool to use in the first evaluation of hospitalized patients with COVID-19.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:38 |
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| Enthalten in: |
Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia - 38(2021), 6 vom: 16. Dez., Seite 768-773 |
| Sprache: |
Spanisch |
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| Weiterer Titel: |
Importancia del índice neutrófilo-linfocito en su asociación con mortalidad en pacientes con COVID-19: Experiencia en un centro de salud en Argentina |
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| Beteiligte Personen: |
Carreras, Matías [VerfasserIn] |
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| Links: |
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| Themen: |
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| Anmerkungen: |
Date Completed 06.05.2022 Date Revised 19.05.2022 published: Print Citation Status MEDLINE |
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| doi: |
10.4067/s0716-10182021000600768 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM340355433 |
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| 245 | 1 | 0 | |a Importance of the neutrophil-lymphocyte ratio in its association with mortality in patients with COVID-19 |b Experience in a health center in Argentina |
| 246 | 3 | 3 | |a Importancia del índice neutrófilo-linfocito en su asociación con mortalidad en pacientes con COVID-19: Experiencia en un centro de salud en Argentina |
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| 520 | |a BACKGROUND: COVID-19 rapidly progresses to acute respiratory failure and mortality. A pandemic needs an urgent requirement for low-cost and easy-access tools that assess the infection evolution. The neutrophil-lymphocyte ratio (NLR) is an inflammatory biomarker used in several diseases | ||
| 520 | |a AIM: To estimate the association between NLR > 3 with mortality in hospitalized patients with COVID 19 | ||
| 520 | |a METHODS: NLR was analyzed in patients with COVID-19 seen at Hospital Fernandez between March and August 2020. Patients were grouped in those with NLR < 3 and those with NLR > 3. Clinical characteristics and mortality were analyzed and compared between groups. A multivariable regression model was used to estimate the association between NLR > 3 and mortality | ||
| 520 | |a RESULTS: We included 711 patients with COVID-19. In a multivariable regression model, NLR > 3 associated with mortality (OR 3.8; 95% CI 1.05 to 13.7; p 0.04) adjusting by age, days of hospitalization, intensive care requirement, severe pneumonia, C-reactive protein levels, arterial hypertension, and comorbidities | ||
| 520 | |a CONCLUSION: NLR was associated with mortality, and it is an accessible and easy tool to use in the first evaluation of hospitalized patients with COVID-19 | ||
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| 700 | 1 | |a Gastaldi, María Victoria |e verfasserin |4 aut | |
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| 700 | 1 | |a Marovelli, Lorenzo |e verfasserin |4 aut | |
| 700 | 1 | |a Gandino, Ignacio Javier |e verfasserin |4 aut | |
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