The effects of carbogen and hyperbaric oxygen treatment on fracture healing in rats
BACKGROUND: Bone fractures and fracture healing are one of the most common problems among orthopedic surgeons. In this study, we investigated the effects of hyperbaric oxygen (HBO) and carbogen (C) treatment on fracture healing in the experimental animal model.
METHODS: Twenty-four male Wistar-Albino rats were randomly divided into three groups as Group 1 (C inhalation therapy), Group 2 (HBO inhalation therapy), and Group 3 (control group), with eight rats in each group. HBO and C treatment were given to the rats in Group 1 and Group 2 1 week before the surgical procedure and 3 weeks after the surgical procedure. Following the surgical procedure, all rats were killed at the end of the 3rd week and the healing tissue in the fracture line was evaluated clinically, radiologically, and histopathologically.
RESULTS: Although there were higher histopathological, radiological, and clinical scores in the HBO and C groups in terms of frac-ture healing compared to the control group, there was no statistically significant difference between the groups.
CONCLUSION: There are many studies in the literature that examine the systemic and local effects of HBO and C treatments and show that they increase tissue oxygenation. Our study showed that HBO and C groups had no beneficial or harmful effects on fracture healing compared to the control group.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:28 |
|---|---|
| Enthalten in: |
Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES - 28(2022), 4 vom: 01. Apr., Seite 411-417 |
| Sprache: |
Englisch |
|---|
| Weiterer Titel: |
Sıçanlarda karbojen ve hiperbarik oksijen tedavisinin kırık iyileşmesine etkileri |
|---|
| Beteiligte Personen: |
Menendi, Umman [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
142M471B3J |
|---|
| Anmerkungen: |
Date Completed 02.05.2022 Date Revised 03.10.2023 published: Print Citation Status MEDLINE |
|---|
| doi: |
10.14744/tjtes.2021.02575 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM340143363 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM340143363 | ||
| 003 | DE-627 | ||
| 005 | 20231226004457.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231226s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.14744/tjtes.2021.02575 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1133.xml |
| 035 | |a (DE-627)NLM340143363 | ||
| 035 | |a (NLM)35485502 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Menendi, Umman |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The effects of carbogen and hyperbaric oxygen treatment on fracture healing in rats |
| 246 | 3 | 3 | |a Sıçanlarda karbojen ve hiperbarik oksijen tedavisinin kırık iyileşmesine etkileri |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 02.05.2022 | ||
| 500 | |a Date Revised 03.10.2023 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a BACKGROUND: Bone fractures and fracture healing are one of the most common problems among orthopedic surgeons. In this study, we investigated the effects of hyperbaric oxygen (HBO) and carbogen (C) treatment on fracture healing in the experimental animal model | ||
| 520 | |a METHODS: Twenty-four male Wistar-Albino rats were randomly divided into three groups as Group 1 (C inhalation therapy), Group 2 (HBO inhalation therapy), and Group 3 (control group), with eight rats in each group. HBO and C treatment were given to the rats in Group 1 and Group 2 1 week before the surgical procedure and 3 weeks after the surgical procedure. Following the surgical procedure, all rats were killed at the end of the 3rd week and the healing tissue in the fracture line was evaluated clinically, radiologically, and histopathologically | ||
| 520 | |a RESULTS: Although there were higher histopathological, radiological, and clinical scores in the HBO and C groups in terms of frac-ture healing compared to the control group, there was no statistically significant difference between the groups | ||
| 520 | |a CONCLUSION: There are many studies in the literature that examine the systemic and local effects of HBO and C treatments and show that they increase tissue oxygenation. Our study showed that HBO and C groups had no beneficial or harmful effects on fracture healing compared to the control group | ||
| 650 | 4 | |a Journal Article | |
| 650 | 7 | |a Carbon Dioxide |2 NLM | |
| 650 | 7 | |a 142M471B3J |2 NLM | |
| 650 | 7 | |a carbogen |2 NLM | |
| 650 | 7 | |a 8063-77-2 |2 NLM | |
| 650 | 7 | |a Oxygen |2 NLM | |
| 650 | 7 | |a S88TT14065 |2 NLM | |
| 700 | 1 | |a Nusran, Gürdal |e verfasserin |4 aut | |
| 700 | 1 | |a Kaymaz, Burak |e verfasserin |4 aut | |
| 700 | 1 | |a Tıskaoğlu, Ramazan |e verfasserin |4 aut | |
| 700 | 1 | |a Yılmaz, Onur |e verfasserin |4 aut | |
| 700 | 1 | |a Canbey Goret, Ceren |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES |d 2003 |g 28(2022), 4 vom: 01. Apr., Seite 411-417 |w (DE-627)NLM123640164 |x 1307-7945 |7 nnns |
| 773 | 1 | 8 | |g volume:28 |g year:2022 |g number:4 |g day:01 |g month:04 |g pages:411-417 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.14744/tjtes.2021.02575 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 28 |j 2022 |e 4 |b 01 |c 04 |h 411-417 | ||