Spontaneous suprachoroidal haemorrhage in haemophilia coincident with ChAdOx1 nCoV-19 vaccine

PURPOSE: To report a case of spontaneous suprachoroidal haemorrhage in a haemophilia patient immediately following ChAdOx1 nCoV-19 vaccination.

CASE PRESENTATION: A 60-year-old man with haemophilia developed painful vision loss in his left eye a day following the ChAdOx1 nCoV-19 vaccination due to acute angle-closure glaucoma from a massive suprachoroidal haemorrhage. He had an extremely deranged coagulation profile; activated partial thromboplastin time (APTT): 89 s, normal range 29-35 s After factor VIII transfusion, ocular hypotensive therapy and systemic/topical steroids, the suprachoroidal haemorrhage and glaucoma resolved, but the vision remained poor.

CONCLUSION: Spontaneous suprachoroidal haemorrhage may be seen in haemophiliacs with deranged coagulation profiles. In our case, it followed ChAdOx1 nCoV-19 vaccination, and we recommend caution and checking the coagulation profile in such patients apriori.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:33

Enthalten in:

European journal of ophthalmology - 33(2023), 4 vom: 01. Juli, Seite NP59-NP61

Sprache:

Englisch

Beteiligte Personen:

Behera, Geeta [VerfasserIn]
Jossy, Ajax [VerfasserIn]
Deb, Amit Kumar [VerfasserIn]
Neelakandan, Siddharth [VerfasserIn]
Basavarajegowda, Abhishek [VerfasserIn]

Links:

Volltext

Themen:

Acute angle-closure glaucoma
B5S3K2V0G8
Case Reports
ChAdOx1 nCoV-19
ChAdOx1 nCoV-19 vaccine
Factor VIII
Haemophilia
Journal Article
Suprachoroidal haemorrhage

Anmerkungen:

Date Completed 10.07.2023

Date Revised 18.07.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1177/11206721221098207

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM340136561