Misidentification of epithelial renal tubular cells as decoy cells in the urinary sediment of a kidney transplant recipient : the importance of adequate clinical information
Copyright © 2022 Elsevier B.V. All rights reserved..
The examination of the urinary sediment of a kidney transplant recipient, carried out in blind conditions, showed the presence of a moderate number of cells which were identified as decoy cells. Most frequently these cells are a marker of BK polyomavirus reactivation, which can lead to BK virus nephropathy and graft loss. However, the patient's clinical history, the absence of BK viremia, and the renal biopsy findings excluded this condition. The careful examination of the renal biopsy demonstrated a severe tubular damage with cells resembling those identified in the urine as decoy cells. This paper is the first which demonstrates that damaged renal tubular epithelial cells can be misidentified as decoy cells. In addition, it highlights the importance of supplying adequate clinical information for a correct urinary sediment examination.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:531 |
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| Enthalten in: |
Clinica chimica acta; international journal of clinical chemistry - 531(2022) vom: 01. Juni, Seite 273-276 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Malvica, Silvia [VerfasserIn] |
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| Links: |
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| Themen: |
BK polyomavirus |
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| Anmerkungen: |
Date Completed 06.06.2022 Date Revised 06.06.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.cca.2022.04.015 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
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| 520 | |a Copyright © 2022 Elsevier B.V. All rights reserved. | ||
| 520 | |a The examination of the urinary sediment of a kidney transplant recipient, carried out in blind conditions, showed the presence of a moderate number of cells which were identified as decoy cells. Most frequently these cells are a marker of BK polyomavirus reactivation, which can lead to BK virus nephropathy and graft loss. However, the patient's clinical history, the absence of BK viremia, and the renal biopsy findings excluded this condition. The careful examination of the renal biopsy demonstrated a severe tubular damage with cells resembling those identified in the urine as decoy cells. This paper is the first which demonstrates that damaged renal tubular epithelial cells can be misidentified as decoy cells. In addition, it highlights the importance of supplying adequate clinical information for a correct urinary sediment examination | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a BK polyomavirus | |
| 650 | 4 | |a Decoy cells | |
| 650 | 4 | |a Kidney transplant | |
| 650 | 4 | |a Renal tubular epithelial cells | |
| 650 | 4 | |a Urinary sediment | |
| 700 | 1 | |a Mateus, Catarina |e verfasserin |4 aut | |
| 700 | 1 | |a Garigali, Giuseppe |e verfasserin |4 aut | |
| 700 | 1 | |a Castellano, Giuseppe |e verfasserin |4 aut | |
| 700 | 1 | |a Fogazzi, Giovanni B |e verfasserin |4 aut | |
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