Endothelial Dysfunction in Systemic Lupus Erythematosus and Systemic Sclerosis : A Common Trigger for Different Microvascular Diseases
Copyright © 2022 Moschetti, Piantoni, Vizzardi, Sciatti, Riccardi, Franceschini and Cavazzana..
This review describes the complex interplay between inflammation, vasculopathy and fibrosis that involve the heart and peripheral small vessels, leading to endothelial stiffness, vascular damage, and early aging in patients with systemic lupus erythematosus and systemic sclerosis, which represents two different models of vascular dysfunction among systemic autoimmune diseases. In fact, despite the fact that diagnostic methods and therapies have been significantly improved in the last years, affected patients show an excess of cardiovascular mortality if compared with the general population. In addition, we provide a complete overview on the new techniques which are used for the evaluation of endothelial dysfunction in a preclinical phase, which could represent a new approach in the assessment of cardiovascular risk in these patients.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2022 |
---|---|
Erschienen: |
2022 |
Enthalten in: |
Zur Gesamtaufnahme - volume:9 |
---|---|
Enthalten in: |
Frontiers in medicine - 9(2022) vom: 15., Seite 849086 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Moschetti, Liala [VerfasserIn] |
---|
Links: |
---|
Themen: |
Endothelial dysfunction |
---|
Anmerkungen: |
Date Revised 16.07.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
---|
doi: |
10.3389/fmed.2022.849086 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM339921056 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM339921056 | ||
003 | DE-627 | ||
005 | 20231226003958.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231226s2022 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.3389/fmed.2022.849086 |2 doi | |
028 | 5 | 2 | |a pubmed24n1133.xml |
035 | |a (DE-627)NLM339921056 | ||
035 | |a (NLM)35462989 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Moschetti, Liala |e verfasserin |4 aut | |
245 | 1 | 0 | |a Endothelial Dysfunction in Systemic Lupus Erythematosus and Systemic Sclerosis |b A Common Trigger for Different Microvascular Diseases |
264 | 1 | |c 2022 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Revised 16.07.2022 | ||
500 | |a published: Electronic-eCollection | ||
500 | |a Citation Status PubMed-not-MEDLINE | ||
520 | |a Copyright © 2022 Moschetti, Piantoni, Vizzardi, Sciatti, Riccardi, Franceschini and Cavazzana. | ||
520 | |a This review describes the complex interplay between inflammation, vasculopathy and fibrosis that involve the heart and peripheral small vessels, leading to endothelial stiffness, vascular damage, and early aging in patients with systemic lupus erythematosus and systemic sclerosis, which represents two different models of vascular dysfunction among systemic autoimmune diseases. In fact, despite the fact that diagnostic methods and therapies have been significantly improved in the last years, affected patients show an excess of cardiovascular mortality if compared with the general population. In addition, we provide a complete overview on the new techniques which are used for the evaluation of endothelial dysfunction in a preclinical phase, which could represent a new approach in the assessment of cardiovascular risk in these patients | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Review | |
650 | 4 | |a endothelial dysfunction | |
650 | 4 | |a microvascular disease | |
650 | 4 | |a systemic lupus erythematosus | |
650 | 4 | |a systemic sclerosis | |
650 | 4 | |a techniques of assessment | |
700 | 1 | |a Piantoni, Silvia |e verfasserin |4 aut | |
700 | 1 | |a Vizzardi, Enrico |e verfasserin |4 aut | |
700 | 1 | |a Sciatti, Edoardo |e verfasserin |4 aut | |
700 | 1 | |a Riccardi, Mauro |e verfasserin |4 aut | |
700 | 1 | |a Franceschini, Franco |e verfasserin |4 aut | |
700 | 1 | |a Cavazzana, Ilaria |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Frontiers in medicine |d 2014 |g 9(2022) vom: 15., Seite 849086 |w (DE-627)NLM245390847 |x 2296-858X |7 nnns |
773 | 1 | 8 | |g volume:9 |g year:2022 |g day:15 |g pages:849086 |
856 | 4 | 0 | |u http://dx.doi.org/10.3389/fmed.2022.849086 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 9 |j 2022 |b 15 |h 849086 |