Development of a Predictive Model for the Diagnosis of Lower Urinary Tract Obstruction in Men
PURPOSE: We sought to develop and validate a bladder outlet obstruction predictive model for men with nonneurogenic lower urinary tract symptoms.
MATERIALS AND METHODS: We retrospectively included 1,148 patients who underwent a urodynamic study in the Urology Service of the Burgos University Hospital from January 2007 to December 2019. Obstruction was defined using the Abrams-Griffiths number. A multivariable logistic regression analysis was conducted to determine the predictors of bladder outlet obstruction. We transferred these data to a model to calculate the individual probability of obstruction.
RESULTS: A first group with 563 patients randomly divided was selected for the design of the predictive risk model and a second group of 585 patients for the validation. A total of 331 patients (58.8%) in the development group and 381 (65.1%) in the validation group had a diagnosis of obstruction. A multivariable logistic regression model showed that age, history of previous surgical intervention, presence of voiding symptoms, preserved anal tone, maximum urinary flow rate and voiding efficiency were significant for predicting obstruction. The model had an area under the receiver operating characteristic curve of 0.78 (95% CI 0.75-0.82) and a model validation of 0.78 (0.72-0.83).
CONCLUSIONS: Our proposed model based on clinical and noninvasive urodynamics parameters allows us to predict the risk of presenting bladder outlet obstruction in patients with lower urinary tract symptoms.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:208 |
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| Enthalten in: |
The Journal of urology - 208(2022), 3 vom: 22. Sept., Seite 668-675 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
de la Cruz Martín, Beatriz [VerfasserIn] |
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| Links: |
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| Themen: |
Diagnosis |
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| Anmerkungen: |
Date Completed 10.08.2022 Date Revised 11.08.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1097/JU.0000000000002721 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM339810645 |
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| 100 | 1 | |a de la Cruz Martín, Beatriz |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Development of a Predictive Model for the Diagnosis of Lower Urinary Tract Obstruction in Men |
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| 500 | |a Date Completed 10.08.2022 | ||
| 500 | |a Date Revised 11.08.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a PURPOSE: We sought to develop and validate a bladder outlet obstruction predictive model for men with nonneurogenic lower urinary tract symptoms | ||
| 520 | |a MATERIALS AND METHODS: We retrospectively included 1,148 patients who underwent a urodynamic study in the Urology Service of the Burgos University Hospital from January 2007 to December 2019. Obstruction was defined using the Abrams-Griffiths number. A multivariable logistic regression analysis was conducted to determine the predictors of bladder outlet obstruction. We transferred these data to a model to calculate the individual probability of obstruction | ||
| 520 | |a RESULTS: A first group with 563 patients randomly divided was selected for the design of the predictive risk model and a second group of 585 patients for the validation. A total of 331 patients (58.8%) in the development group and 381 (65.1%) in the validation group had a diagnosis of obstruction. A multivariable logistic regression model showed that age, history of previous surgical intervention, presence of voiding symptoms, preserved anal tone, maximum urinary flow rate and voiding efficiency were significant for predicting obstruction. The model had an area under the receiver operating characteristic curve of 0.78 (95% CI 0.75-0.82) and a model validation of 0.78 (0.72-0.83) | ||
| 520 | |a CONCLUSIONS: Our proposed model based on clinical and noninvasive urodynamics parameters allows us to predict the risk of presenting bladder outlet obstruction in patients with lower urinary tract symptoms | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a diagnosis | |
| 650 | 4 | |a lower urinary tract symptoms; models, statistical | |
| 650 | 4 | |a urinary bladder neck obstruction | |
| 700 | 1 | |a Adot Zurbano, José M |e verfasserin |4 aut | |
| 700 | 1 | |a Gutiérrez-Mínguez, Emilio |e verfasserin |4 aut | |
| 700 | 1 | |a Gómez Sánchez, Esther |e verfasserin |4 aut | |
| 700 | 1 | |a Calvo, Sara |e verfasserin |4 aut | |
| 700 | 1 | |a Tamayo Gómez, Eduardo |e verfasserin |4 aut | |
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