Diagnosis of congenital infections in premature, low-birthweight newborns with intrauterine growth restriction caused by cytomegalovirus (CMV), herpes simplex virus (HSV), Parvo-B 19, and Zika virus : a systematic review

© 2022 Walter de Gruyter GmbH, Berlin/Boston..

OBJECTIVES: To identify the prevalence of viral congenital infections in newborns classified as premature, low-birthweight, small for gestational age or intrauterine growth restriction.

METHODS: The definition considered for selecting papers were: P as newborns younger than 28 days; V as low-birthweight, prematurity and intrauterine growth restriction; O as frequency of congenital infections with Cytomegalovirus, Parvovirus B19, Herpes Simplex, and Zika virus. The research was performed using EMBASE, LILACS, SCOPUS and MEDLINE databases, with no limitations on date and language.

RESULTS: Eight studies were included. Manuscripts including Herpes Simplex, Zika virus or Parvovirus B19 did not fulfill the defined criteria. A wide variation in the frequency of CMV congenital infection (0-4.8%) was found, which might be attributed to regional and methodological differences between investigations.

CONCLUSIONS: Newborn characteristics associated with CMV congenital infections may direct investigations towards these patients with a higher probability of infection. However, as data are controversial, studies concerning screening of infection are important to define recommendations of diagnosis.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:50

Enthalten in:

Journal of perinatal medicine - 50(2022), 7 vom: 27. Sept., Seite 993-1000

Sprache:

Englisch

Beteiligte Personen:

Lino, Janaina F [VerfasserIn]
Diniz, Lilian M O [VerfasserIn]
Rezende, Larissa G [VerfasserIn]
Costa, Victoria F T [VerfasserIn]
Romanelli, Roberta M C [VerfasserIn]

Links:

Volltext

Themen:

Congenital infection
Fetal growth retardation
Infant, premature
Infant, small for gestational age
Infant, very low birth weight
Infectious disease transmission, vertical
Journal Article
Systematic Review

Anmerkungen:

Date Completed 13.09.2022

Date Revised 13.09.2022

published: Electronic-Print

Citation Status MEDLINE

doi:

10.1515/jpm-2021-0244

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM339569085