Multiple sclerosis-related fatigue lacks a unified definition : A narrative review
Copyright: © 2022 Journal of Research in Medical Sciences..
Fatigue is the most common symptom in multiple sclerosis (MS). Although MS-related fatigue (MS-F) strongly affects quality of life and social performance of patients, there is currently a lack of knowledge about its pathophysiology, which in turns leads to poor objective diagnosis and management. Recent studies have attempted to explain potential etiologies as well as treatments for MS-F. However, it seems that without a consensus on its nature, these data could not provide a route to a successful approach. In this Article, we review definitions, epidemiology, risk factors and correlated comorbidities, pathophysiology, assessment methods, neuroimaging findings, and pharmacological and nonpharmacological treatments of MS-F. Further studies are warranted to define fatigue in MS patients more accurately, which could result in precise diagnosis and management.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:27 |
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| Enthalten in: |
Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences - 27(2022) vom: 25., Seite 24 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Adibi, Iman [VerfasserIn] |
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| Links: |
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| Themen: |
Diagnosis |
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| Anmerkungen: |
Date Revised 15.04.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.4103/jrms.jrms_1401_20 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM339485671 |
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| 520 | |a Copyright: © 2022 Journal of Research in Medical Sciences. | ||
| 520 | |a Fatigue is the most common symptom in multiple sclerosis (MS). Although MS-related fatigue (MS-F) strongly affects quality of life and social performance of patients, there is currently a lack of knowledge about its pathophysiology, which in turns leads to poor objective diagnosis and management. Recent studies have attempted to explain potential etiologies as well as treatments for MS-F. However, it seems that without a consensus on its nature, these data could not provide a route to a successful approach. In this Article, we review definitions, epidemiology, risk factors and correlated comorbidities, pathophysiology, assessment methods, neuroimaging findings, and pharmacological and nonpharmacological treatments of MS-F. Further studies are warranted to define fatigue in MS patients more accurately, which could result in precise diagnosis and management | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a epidemiology | |
| 650 | 4 | |a etiology | |
| 650 | 4 | |a fatigue | |
| 650 | 4 | |a multiple sclerosis | |
| 650 | 4 | |a neuroimaging | |
| 650 | 4 | |a physiopathology | |
| 650 | 4 | |a risk factors | |
| 650 | 4 | |a therapy | |
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| 700 | 1 | |a Ramezani, Neda |e verfasserin |4 aut | |
| 700 | 1 | |a Pourmohammadi, Ahmad |e verfasserin |4 aut | |
| 700 | 1 | |a Azimzadeh, Kiarash |e verfasserin |4 aut | |
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