Herpes Simplex Virus 1 Anterior Uveitis following Coronavirus Disease 2019 (COVID-19) Vaccination in an Asian Indian Female

PURPOSE: To describe a case of herpes simplex virus 1 (HSV 1) infection following coronavirus disease 2019 (COVID-19) vaccination in an Asian Indian female.

METHODS: Retrospective case report.

RESULT: A 40-year-old female presented with decreased vision, pain, and photophobia of 2 weeks duration. She reported receiving the second dose of COVISHIELDTM (ChAdOx1-S [recombinant]) 1 week prior to the onset of ocular symptoms. Left eye examination revealed granulomatous anterior uveitis. Aqueous sample from the left eye tested positive for HSV1 by polymerase chain reaction(PCR) method. She was managed with oral antiviral therapy, topical steroids, and cycloplegic agent and showed significant improvement of inflammation within 1 week and resolved within 3 weeks.

CONCLUSION: This report demonstrates a potential association of HSV 1 anterior uveitis with COVID-19 vaccination. A high index of suspicion of viral etiology is warranted when uveitis presents with reduced corneal sensations and pigmented keratic precipitates, following a recent history of COVID-19 vaccination.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:30

Enthalten in:

Ocular immunology and inflammation - 30(2022), 5 vom: 30. Juli, Seite 1260-1264

Sprache:

Englisch

Beteiligte Personen:

Sangoram, Rohini [VerfasserIn]
Mahendradas, Padmamalini [VerfasserIn]
Bhakti Mishra, Sai [VerfasserIn]
Kawali, Ankush [VerfasserIn]
Sanjay, Srinivasan [VerfasserIn]
Shetty, Rohit [VerfasserIn]

Links:

Volltext

Themen:

Anterior uveitis
Antiviral Agents
B5S3K2V0G8
COVID 19 vaccination
COVID-19 Vaccines
Case Reports
ChAdOx1 nCoV-19
Confocal microscopy
DNA, Viral
HSV 1
Herpes simplex virus
Journal Article
Mydriatics

Anmerkungen:

Date Completed 20.10.2022

Date Revised 20.10.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1080/09273948.2022.2055580

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM339343583