Analysis of the most important features of obstructive sleep apnoea
Introduction and objective: Obstructive sleep apnoea results in metabolic and cardiovascular disorders due to inter- mittent hypoxia. The main aim of the present study was to analyze the most important features of obstructive sleep apnoea, using anthropometric measurements and blood tests. Material and method: In this prospective investigation, 100 patients (74 male and 26 female patients, mean age +/- SD years, 42.15 +/- 12.7) were enrolled. These patients were divided into control (n = 36) and obstructive sleep apnoea (n = 64) groups regarding the results of polysomnography. The examination of the patients consisted of detailed anamnestic data, anthropometric measurements, laboratory test and the use of apnoea questionnaires. Results: In the obstructive sleep apnoea group, significantly higher neck (p<0.015), hip and abdomen circumfer- ences and BMI values (p<0.000) were observed. Significantly higher ratio of male patients in the case of obstructive sleep apnoea was detected (p<0.000). In the control group, only the neck circumferences differed significantly be- tween the two genders (p<0.000), but in the obstructive sleep apnoea group the neck (p = 0.001) and abdominal circumferences (p = 0.028) have also differed. Hypertension (64% and 21%) and type 2 diabetes mellitus (6.4% and 0%) were more frequent in the obstructive sleep apnoea group, while cardiovascular disorders (1% and 2.7 %) and gastroesophageal reflux disease (4.71% and 5.42%) in the control group. BMI values were significantly positively cor- related with the neck, abdominal and hip circumferences, both in the control and obstructive sleep apnoea groups. Moreover, in the control group, a significant negative correlation between HDL-cholesterol and BMI, neck and abdominal circumferences was observed. Conclusion: Obesity, as one of the most important risk factors for obstructive sleep apnoea and the intermittent hypo- xia contribute to the development of comorbidities. The diagnosis and therapy of the comorbidities is of great im- portance due to their effects on the patients' quality of life.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:163 |
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| Enthalten in: |
Orvosi hetilap - 163(2022), 15 vom: 10. Apr., Seite 586-592 |
| Sprache: |
Ungarisch |
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| Weiterer Titel: |
Az obstruktív alvási apnoe fobb jellemzoinek vizsgálata |
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| Beteiligte Personen: |
Molnár, Viktória [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 12.04.2022 Date Revised 19.12.2022 published: Electronic-Print Citation Status MEDLINE |
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| doi: |
10.1556/650.2022.32428 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM339284447 |
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| 245 | 1 | 0 | |a Analysis of the most important features of obstructive sleep apnoea |
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| 520 | |a Introduction and objective: Obstructive sleep apnoea results in metabolic and cardiovascular disorders due to inter- mittent hypoxia. The main aim of the present study was to analyze the most important features of obstructive sleep apnoea, using anthropometric measurements and blood tests. Material and method: In this prospective investigation, 100 patients (74 male and 26 female patients, mean age +/- SD years, 42.15 +/- 12.7) were enrolled. These patients were divided into control (n = 36) and obstructive sleep apnoea (n = 64) groups regarding the results of polysomnography. The examination of the patients consisted of detailed anamnestic data, anthropometric measurements, laboratory test and the use of apnoea questionnaires. Results: In the obstructive sleep apnoea group, significantly higher neck (p<0.015), hip and abdomen circumfer- ences and BMI values (p<0.000) were observed. Significantly higher ratio of male patients in the case of obstructive sleep apnoea was detected (p<0.000). In the control group, only the neck circumferences differed significantly be- tween the two genders (p<0.000), but in the obstructive sleep apnoea group the neck (p = 0.001) and abdominal circumferences (p = 0.028) have also differed. Hypertension (64% and 21%) and type 2 diabetes mellitus (6.4% and 0%) were more frequent in the obstructive sleep apnoea group, while cardiovascular disorders (1% and 2.7 %) and gastroesophageal reflux disease (4.71% and 5.42%) in the control group. BMI values were significantly positively cor- related with the neck, abdominal and hip circumferences, both in the control and obstructive sleep apnoea groups. Moreover, in the control group, a significant negative correlation between HDL-cholesterol and BMI, neck and abdominal circumferences was observed. Conclusion: Obesity, as one of the most important risk factors for obstructive sleep apnoea and the intermittent hypo- xia contribute to the development of comorbidities. The diagnosis and therapy of the comorbidities is of great im- portance due to their effects on the patients' quality of life | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a anthropological characteristics | |
| 650 | 4 | |a antropológiai jellemzők | |
| 650 | 4 | |a comorbidities | |
| 650 | 4 | |a diabetes mellitus | |
| 650 | 4 | |a hypertension | |
| 650 | 4 | |a hypertonia | |
| 650 | 4 | |a komorbiditás | |
| 650 | 4 | |a obstructive sleep apnoea | |
| 650 | 4 | |a obstruktív alvási apnoe | |
| 650 | 4 | |a társbetegség | |
| 700 | 1 | |a Molnár, András |e verfasserin |4 aut | |
| 700 | 1 | |a Lakner, Zoltán |e verfasserin |4 aut | |
| 700 | 1 | |a Kunos, László |e verfasserin |4 aut | |
| 700 | 1 | |a Angyal, Emese |e verfasserin |4 aut | |
| 700 | 1 | |a Németh, Fruzsina |e verfasserin |4 aut | |
| 700 | 1 | |a Tamás, László |e verfasserin |4 aut | |
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