The residual effect of coronovirus disease 2019 on olfactory acuity and mucociliary clearance time : a cross-sectional, controlled study

OBJECTIVE: This study evaluated the olfactory, sinonasal and mucociliary functions of patients with post-coronavirus disease 2019 long-term persistent olfactory dysfunction.

METHOD: Three groups of 30 patients each were formed: patients with a history of coronavirus disease 2019 infection with self-reported, persistent, sudden-onset olfactory dysfunction (group 1), patients with a history of coronavirus disease 2019 infection without any self-reported olfactory dysfunction (group 2) and healthy controls with no history of coronavirus disease 2019 infection (group 3). Saccharin time, Sniffin' Sticks, Turkish Nasal Obstruction Symptom Evaluation and Sino-Nasal Outcome Test 22 scores were compared.

RESULTS: Turkish Nasal Obstruction Symptom Evaluation scores were similar between groups (p = 0.252). Sino-Nasal Outcome Test-22 scores were higher in group 1 than groups 2 and 3 (p < 0.01 and p < 0.001, respectively). Saccharin time was significantly longer in group 1 than groups 2 and 3 (p < 0.05 and p < 0.01, respectively). Group 1 had lower olfactory scores than groups 2 and 3 (p < 0.001 and p < 0.001, respectively).

CONCLUSION: Mucociliary clearance time was significantly prolonged in patients with post-coronavirus disease 2019 persistent olfactory dysfunction. Coronavirus disease 2019 infection was likely to cause asymptomatic olfactory dysfunction.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:136

Enthalten in:

The Journal of laryngology and otology - 136(2022), 8 vom: 06. Aug., Seite 742-746

Sprache:

Englisch

Beteiligte Personen:

Kandemir, S [VerfasserIn]
Pamuk, A E [VerfasserIn]

Links:

Volltext

Themen:

Anosmia
COVID-19
FST467XS7D
Journal Article
Mucociliary Clearance
Olfaction Disorders
SARS-CoV-2
Saccharin
Smell

Anmerkungen:

Date Completed 04.08.2022

Date Revised 04.08.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1017/S0022215122000925

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM339127082