Ultrasound-guided epidural anesthesia and sedation for open transvesical Cohen ureteric reimplantation surgery in 20 consecutive children : a prospective case series and proof-of-concept study

BACKGROUND: Epidural anesthesia is usually combined with general anesthesia (GA) for children undergoing sub-umbilical surgery and GA in children is associated with a potential for respiratory events. Aiming to reduce airway manipulation and the use of GA drugs, we designed a study of transvesical Cohen ureteteric reimplantion under epidural anesthesia in sedated, spontaneously breathing children.

METHODS: We enrolled 20 children (3-83 months, 6.3-25.0 kg) scheduled for open transvesical abdominal surgery with Pfannenstiel incision. Sedation was followed by ultrasound-guided epidural anesthesia. Increases in heart rate by >15% and or patient movements upon skin incision were rated as block deficiencies. Intubation equipment for advanced airway management was kept on standby. The primary study endpoint was successful blockade, meaning that no sequential airway management was required for the spontaneous breathing patients during surgery. Secondary endpoints included any use of fentanyl/propofol intraoperatively and of postoperative analgesics in the recovery room.

RESULTS: All 20 blocks were successful, with no block deficiencies upon skin incision, no need for sequential airway management, and stable SpO<inf>2</inf> levels (97-100%). Surgery took a median of 120.5 minutes (IQR: 89.3-136.5) and included one bolus of fentanyl in one patient 120 minutes into a protracted operation. No more systemic analgesia had to be provided in the recovery room.

CONCLUSIONS: Sedation and epidural anesthesia emerged as a useful alternative to GA from our consecutive case series.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:88

Enthalten in:

Minerva anestesiologica - 88(2022), 7-8 vom: 15. Juli, Seite 564-572

Sprache:

Englisch

Beteiligte Personen:

Opfermann, Philipp [VerfasserIn]
Zadrazil, Markus [VerfasserIn]
Tonnhofer, Ursula [VerfasserIn]
Metzelder, Martin [VerfasserIn]
Marhofer, Peter [VerfasserIn]
Schmid, Werner [VerfasserIn]

Links:

Volltext

Themen:

Fentanyl
Journal Article
UF599785JZ

Anmerkungen:

Date Completed 15.07.2022

Date Revised 18.07.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.23736/S0375-9393.22.15904-3

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM339116358