Costs of seasonal influenza vaccination in South Africa

© 2022 The Authors. Influenza and Other Respiratory Viruses published by John Wiley & Sons Ltd..

BACKGROUND: Influenza accounts for a substantial number of deaths and hospitalisations annually in South Africa. To address this disease burden, the South African National Department of Health introduced a trivalent inactivated influenza vaccination programme in 2010.

METHODS: We adapted and populated the WHO Seasonal Influenza Immunization Costing Tool (WHO SIICT) with country-specific data to estimate the cost of the influenza vaccination programme in South Africa. Data were obtained through key-informant interviews at different levels of the health system and through a review of existing secondary data sources. Costs were estimated from a public provider perspective and expressed in 2018 prices. We conducted scenario analyses to assess the impact of different levels of programme expansion and the use of quadrivalent vaccines on total programme costs.

RESULTS: Total financial and economic costs were estimated at approximately USD 2.93 million and USD 7.91 million, respectively, while financial and economic cost per person immunised was estimated at USD 3.29 and USD 8.88, respectively. Expanding the programme by 5% and 10% increased economic cost per person immunised to USD 9.36 and USD 9.52 in the two scenarios, respectively. Finally, replacing trivalent inactivated influenza vaccine (TIV) with quadrivalent vaccine increased financial and economic costs to USD 4.89 and USD 10.48 per person immunised, respectively.

CONCLUSION: We adapted the WHO SIICT and provide estimates of the total costs of the seasonal influenza vaccination programme in South Africa. These estimates provide a basis for planning future programme expansion and may serve as inputs for cost-effectiveness analyses of seasonal influenza vaccination programmes.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:16

Enthalten in:

Influenza and other respiratory viruses - 16(2022), 5 vom: 13. Sept., Seite 873-880

Sprache:

Englisch

Beteiligte Personen:

Fraser, Heather [VerfasserIn]
Tombe-Mdewa, Winfrida [VerfasserIn]
Kohli-Lynch, Ciaran [VerfasserIn]
Hofman, Karen [VerfasserIn]
Tempia, Stefano [VerfasserIn]
McMorrow, Meredith [VerfasserIn]
Lambach, Philipp [VerfasserIn]
Ramkrishna, Wayne [VerfasserIn]
Cohen, Cheryl [VerfasserIn]
Hutubessy, Raymond [VerfasserIn]
Edoka, Ijeoma [VerfasserIn]

Links:

Volltext

Themen:

Cost analysis
Health care economics
Influenza Vaccines
Influenza vaccine
Journal Article
Preventive health programmes
Research Support, Non-U.S. Gov't
Review
South Africa

Anmerkungen:

Date Completed 03.08.2022

Date Revised 03.09.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1111/irv.12987

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM338854355