A systematic review on mucocutaneous presentations after COVID-19 vaccination and expert recommendations about vaccination of important immune-mediated dermatologic disorders

© 2022 Wiley Periodicals LLC..

With dermatologic side effects being fairly prevalent following vaccination against COVID-19, and the multitude of studies aiming to report and analyze these adverse events, the need for an extensive investigation on previous studies seemed urgent, in order to provide a thorough body of information about these post-COVID-19 immunization mucocutaneous reactions. To achieve this goal, a comprehensive electronic search was performed through the international databases including Medline (PubMed), Scopus, Cochrane, Web of science, and Google scholar on July 12, 2021, and all articles regarding mucocutaneous manifestations and considerations after COVID-19 vaccine administration were retrieved using the following keywords: COVID-19 vaccine, dermatology considerations and mucocutaneous manifestations. A total of 917 records were retrieved and a final number of 180 articles were included in data extraction. Mild, moderate, severe and potentially life-threatening adverse events have been reported following immunization with COVID vaccines, through case reports, case series, observational studies, randomized clinical trials, and further recommendations and consensus position papers regarding vaccination. In this systematic review, we categorized these results in detail into five elaborate tables, making what we believe to be an extensively informative, unprecedented set of data on this topic. Based on our findings, in the viewpoint of the pros and cons of vaccination, mucocutaneous adverse events were mostly non-significant, self-limiting reactions, and for the more uncommon moderate to severe reactions, guidelines and consensus position papers could be of great importance to provide those at higher risks and those with specific worries of flare-ups or inefficient immunization, with sufficient recommendations to safely schedule their vaccine doses, or avoid vaccination if they have the discussed contra-indications.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:35

Enthalten in:

Dermatologic therapy - 35(2022), 6 vom: 22. Juni, Seite e15461

Sprache:

Englisch

Beteiligte Personen:

Seirafianpour, Farnoosh [VerfasserIn]
Pourriyahi, Homa [VerfasserIn]
Gholizadeh Mesgarha, Milad [VerfasserIn]
Pour Mohammad, Arash [VerfasserIn]
Shaka, Zoha [VerfasserIn]
Goodarzi, Azadeh [VerfasserIn]

Links:

Volltext

Themen:

Acute
Adverse effect
Adverse event
Adverse event following immunization
Allergy
Angioedema
AstraZeneca
AstraZeneca/Oxford
Atopic dermatitis
Bharat
COVID-19 Vaccines
COVID-19 vaccine
Collagen vascular disease
Comirnaty
Cutaneous
Cyanosis
Delayed
Delayed-type hypersensitivity
Dermatology
Ecchymosis
Edema
Erythema multiforme
Exanthematous rash
Herpes
Hidradenitis suppurativa
Inflammatory bowel disease
Injection site reaction
Janssen
Johnson & Johnson
Journal Article
Late
Local site reaction
Maculopapular rash
Mastocytosis
Moderna
Morbilliform rash
Mucocutaneous
Mucosal
Pemphigoid
Pemphigus
Pernio
Petechia
Pfizer
Pfizer-BioNTech
Pityriasis rosea
Pruritus
Psoriasis
Purpura
Remote site reaction
Review
Rheumatic disorders
SARS-Cov-2
Side effect
Sinopharm
Sinovac
Sputnik
Systematic Review
Urticaria
Vaccine
Vaccine Adverse Event Reporting System
Zoster

Anmerkungen:

Date Completed 08.06.2022

Date Revised 15.09.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1111/dth.15461

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM338469451