Recurrence of tubercular choroiditis following anti-SARS-CoV-2 vaccination

PURPOSE: To report recurrence of tubercular choroiditis following anti-SARS-CoV-2 vaccination in two patients with quiescent disease activity for more than a year.

METHODS: Retrospective observational case reports.

RESULTS: Two patients (one female and one male) under follow-up for posterior uveitis having stable course with absence of ocular inflammation for more than a year presented with recurrence of choroiditis lesions 2-6 weeks following anti-SARS-CoV-2 vaccination. Both the patients were managed with intravitreal dexamethasone implant (Ozurdex®, Allergan, Inc., Irvine, CA, USA) and showed resolution of choroiditis lesions upon follow-up.

CONCLUSIONS: Acute onset recurrence of inflammation, in absence of any change in health status or treatment suggests the potential role of vaccination being the trigger of this reactivation. Given large-scale vaccination against novel coronavirus- SARS-CoV-2, careful vigilance is warranted to pick up the disease recurrence in patients with posterior uveitis.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:33

Enthalten in:

European journal of ophthalmology - 33(2023), 3 vom: 09. Mai, Seite NP118-NP121

Sprache:

Englisch

Beteiligte Personen:

Arora, Atul [VerfasserIn]
Handa, Sabia [VerfasserIn]
Singh, Simar Rajan [VerfasserIn]
Sharma, Aman [VerfasserIn]
Bansal, Reema [VerfasserIn]
Agrawal, Rupesh [VerfasserIn]
Gupta, Vishali [VerfasserIn]

Links:

Volltext

Themen:

7S5I7G3JQL
Choroidal/retinal inflammation
Dexamethasone
IMMUNOLOGY
Immunology
Journal Article
Posterior uveitis
RETINA
UVEA
UVEITIS

Anmerkungen:

Date Completed 01.05.2023

Date Revised 01.05.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1177/11206721221088439

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM338374396