A Novel Solid-State PVC-Membrane Potentiometric Dopamine-Selective Sensor Based on Molecular Imprinted Polymer
A novel solid-state polyvinylchloride (PVC) membrane potentiometric dopamine-selective microsensor was constructed based upon dopamine-imprinted polymer used as the ionophore in the membrane structure. The optimum membrane composition was determined as 4% (w/w) MIP, 69% (w/w) bis(2-ethylhexyl) sebacate (DOS), 26% (w/w) PVC, and 1% (w/w) potassiumtetrakis(4-chlorophenyl) borate (KTpClPB). The detection limit of the microsensor was determined to be 3.71×10-7 mol.L-1. The microsensor exhibited a super-Nernstian response for dopamine over the concentration range of 10-6-10-1 mol.L-1, with a short response time (<15 s) and a slope of 60.3±1.3 mV per decade (R2: 0.9998) over seven weeks. The microsensor was effectively performed in a pH range of 4.0-8.0 and a temperature range of 5-30 °C. The microsensor has been successfully demonstrated for the rapid, accurate, selective and reproducible determination of dopamine in pharmaceutical formulations with the recovery of 104.3-104.8%. The obtained results were in good harmony with the UV-Vis results at a confidence level of 95%.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:69 |
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| Enthalten in: |
Acta chimica Slovenica - 69(2022), 1 vom: 15. März, Seite 108-115 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Dere, Nurşen [VerfasserIn] |
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| Links: |
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| Themen: |
9002-86-2 |
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| Anmerkungen: |
Date Completed 21.03.2022 Date Revised 21.03.2022 published: Electronic Citation Status MEDLINE |
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| doi: |
10.17344/acsi.2021.7053 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM338286632 |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a A novel solid-state polyvinylchloride (PVC) membrane potentiometric dopamine-selective microsensor was constructed based upon dopamine-imprinted polymer used as the ionophore in the membrane structure. The optimum membrane composition was determined as 4% (w/w) MIP, 69% (w/w) bis(2-ethylhexyl) sebacate (DOS), 26% (w/w) PVC, and 1% (w/w) potassiumtetrakis(4-chlorophenyl) borate (KTpClPB). The detection limit of the microsensor was determined to be 3.71×10-7 mol.L-1. The microsensor exhibited a super-Nernstian response for dopamine over the concentration range of 10-6-10-1 mol.L-1, with a short response time (<15 s) and a slope of 60.3±1.3 mV per decade (R2: 0.9998) over seven weeks. The microsensor was effectively performed in a pH range of 4.0-8.0 and a temperature range of 5-30 °C. The microsensor has been successfully demonstrated for the rapid, accurate, selective and reproducible determination of dopamine in pharmaceutical formulations with the recovery of 104.3-104.8%. The obtained results were in good harmony with the UV-Vis results at a confidence level of 95% | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a all-solid-state microsensor | |
| 650 | 4 | |a dopamine | |
| 650 | 4 | |a molecular imprinted polymer | |
| 650 | 4 | |a potentiometry | |
| 650 | 7 | |a Ionophores |2 NLM | |
| 650 | 7 | |a Polymers |2 NLM | |
| 650 | 7 | |a Polyvinyl Chloride |2 NLM | |
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| 650 | 7 | |a Dopamine |2 NLM | |
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| 700 | 1 | |a Yolcu, Murat |e verfasserin |4 aut | |
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