A Retrospective Population-Based Survival Study of Idiopathic Pulmonary Arterial Hypertension in Korea
© 2022 The Korean Academy of Medical Sciences..
BACKGROUND: Few studies used nationwide data to assess the survival rates (SRs) and death risk for idiopathic pulmonary arterial hypertension (IPAH; ICD-10 I27.0) in Korea.
METHODS: IPAH data (N = 9,017; female:male = 6:4) were collected from the National Health Insurance Service in Korea, from 2006 through 2017. The data consisted of primary diagnoses related to IPAH. The Kaplan-Meier method and Cox proportional-hazards analyses were carried out.
RESULTS: The mean age was 62.3 (± 19.4) years, 64.2 (± 18.9) years in female and 59.4 (± 19.8) years in male (P < 0.001). The one-, three-, five- and 10-year SRs for IPAH were 89.0%, 79.8%, 72.3% and 57.0%, respectively. The adjusted hazard ratio (HR) of IPAH was 1.81 (95% confidence interval [CI], 1.26-2.59) in 60-69 age group, 3.42 (95% CI, 2.40-4.87) in 70-79, and 7.73 (95% CI, 5.43-11.0) in 80s. Other risk factors were male, low-income status, diabetes, myocardial infarction, atrial fibrillation, ischemic stroke, hemorrhagic stroke, and malignant neoplasm.
CONCLUSION: The 10-year SR of IPAH was 57% in Korea. The HR for IPAH was significantly high in patients with older age and other risk factors.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:37 |
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| Enthalten in: |
Journal of Korean medical science - 37(2022), 10 vom: 14. März, Seite e80 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Jang, Shin Yi [VerfasserIn] |
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| Links: |
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| Themen: |
Causes of Death |
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| Anmerkungen: |
Date Completed 04.04.2022 Date Revised 05.04.2022 published: Electronic Citation Status MEDLINE |
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| doi: |
10.3346/jkms.2022.37.e80 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM338198563 |
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| 245 | 1 | 2 | |a A Retrospective Population-Based Survival Study of Idiopathic Pulmonary Arterial Hypertension in Korea |
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| 500 | |a Date Revised 05.04.2022 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2022 The Korean Academy of Medical Sciences. | ||
| 520 | |a BACKGROUND: Few studies used nationwide data to assess the survival rates (SRs) and death risk for idiopathic pulmonary arterial hypertension (IPAH; ICD-10 I27.0) in Korea | ||
| 520 | |a METHODS: IPAH data (N = 9,017; female:male = 6:4) were collected from the National Health Insurance Service in Korea, from 2006 through 2017. The data consisted of primary diagnoses related to IPAH. The Kaplan-Meier method and Cox proportional-hazards analyses were carried out | ||
| 520 | |a RESULTS: The mean age was 62.3 (± 19.4) years, 64.2 (± 18.9) years in female and 59.4 (± 19.8) years in male (P < 0.001). The one-, three-, five- and 10-year SRs for IPAH were 89.0%, 79.8%, 72.3% and 57.0%, respectively. The adjusted hazard ratio (HR) of IPAH was 1.81 (95% confidence interval [CI], 1.26-2.59) in 60-69 age group, 3.42 (95% CI, 2.40-4.87) in 70-79, and 7.73 (95% CI, 5.43-11.0) in 80s. Other risk factors were male, low-income status, diabetes, myocardial infarction, atrial fibrillation, ischemic stroke, hemorrhagic stroke, and malignant neoplasm | ||
| 520 | |a CONCLUSION: The 10-year SR of IPAH was 57% in Korea. The HR for IPAH was significantly high in patients with older age and other risk factors | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Causes of Death | |
| 650 | 4 | |a Death | |
| 650 | 4 | |a Idiopathic Pulmonary Arterial Hypertension | |
| 650 | 4 | |a Risk | |
| 650 | 4 | |a Survival Rates | |
| 700 | 1 | |a Kim, Eun Kyoung |e verfasserin |4 aut | |
| 700 | 1 | |a Huh, June |e verfasserin |4 aut | |
| 700 | 1 | |a Song, Jinyoung |e verfasserin |4 aut | |
| 700 | 1 | |a Kang, I-Seok |e verfasserin |4 aut | |
| 700 | 1 | |a Park, Seung Woo |e verfasserin |4 aut | |
| 700 | 1 | |a Kim, Duk-Kyung |e verfasserin |4 aut | |
| 700 | 1 | |a Chang, Sung-A |e verfasserin |4 aut | |
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