Regression of diffuse large B-cell lymphoma after discontinuation of salazosulfapyridine

An 81-year-old man with a 3-year history of salazosulfapyridine (SASP) therapy for rheumatoid arthritis (RA) presented with pulmonary infiltrates and underwent computed tomography-guided biopsy. The histopathological and immunohistochemical evaluation confirmed the diagnosis of diffuse large B-cell lymphoma (DLBCL). He was recommended chemotherapy, which he refused. Due to the possibility of other iatrogenic immunodeficiency-associated lymphoproliferative disorders, SASP therapy was discontinued. SASP therapy withdrawal led to near-complete resolution of the lung infiltration shadows, and the serum soluble interleukin 2 receptor level returned to the normal range. This is the first report of a case of remission of DLBCL, following SASP therapy withdrawal in a patient with RA.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:63

Enthalten in:

Rinsho ketsueki] The Japanese journal of clinical hematology - 63(2022), 2 vom: 20., Seite 99-103

Sprache:

Japanisch

Beteiligte Personen:

Yoshinaga, Noriyoshi [VerfasserIn]
Oka, Satoshi [VerfasserIn]
Asagoe, Kohsuke [VerfasserIn]

Links:

Volltext

Themen:

3XC8GUZ6CB
Case Reports
Diffuse large B-cell lymphoma
Journal Article
Other iatrogenic immunodeficiency-associated lymphoproliferative disorders
Rheumatoid arthritis
Salazosulfapyridine
Sulfasalazine

Anmerkungen:

Date Completed 11.03.2022

Date Revised 11.03.2022

published: Print

Citation Status MEDLINE

doi:

10.11406/rinketsu.63.99

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM337953848