A case of cerebral venous sinus thrombosis following the vaccination with Tozinameran

A 31-year-old man visited our hospital due to experiencing severe headaches, vomiting, and hypesthesia in the left side of his body. He had no past illnesses and had had no severe headaches before. The symptoms started the day after receiving the coronavirus disease 2019 (COVID-19) vaccination with Tozinameran. An MRI revealed cerebral venous sinus thrombosis and high intensity (DWI & FLAIR) of the right thalamus. Anticoagulant therapy was initiated, and his symptoms improved gradually. The follow-up MRI showed recanalization in a large part of the occluded venous sinuses. Most of the coagulation tests were normal, except for slightly high value of D-dimer, and the polymerase chain reaction (PCR) test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was negative. Further cases are needed to judge if there is some sort of relationship between the vaccination and the cerebral venous sinus thrombosis.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:62

Enthalten in:

Rinsho shinkeigaku = Clinical neurology - 62(2022), 3 vom: 29. März, Seite 184-189

Sprache:

Japanisch

Beteiligte Personen:

Iwakami, Takayuki [VerfasserIn]
Yamada, So [VerfasserIn]
Ogasawara, Yoshifumi [VerfasserIn]
Son, Jaehyun [VerfasserIn]

Links:

Volltext

Themen:

Case Reports
Cerebral venous sinus thrombosis
Coronavirus disease 2019 (COVID-19) vaccine
Journal Article
Tozinameran

Anmerkungen:

Date Completed 06.04.2022

Date Revised 06.04.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.5692/clinicalneurol.cn-001656

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM337598541