The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology

© 2022. The Author(s)..

There is a growing need for systems that efficiently support the work of medical teams at the precision-oncology point of care. Here, we present the implementation of the Molecular Tumor Board Portal (MTBP), an academic clinical decision support system developed under the umbrella of Cancer Core Europe that creates a unified legal, scientific and technological platform to share and harness next-generation sequencing data. Automating the interpretation and reporting of sequencing results decrease the need for time-consuming manual procedures that are prone to errors. The adoption of an expert-agreed process to systematically link tumor molecular profiles with clinical actions promotes consistent decision-making and structured data capture across the connected centers. The use of information-rich patient reports with interactive content facilitates collaborative discussion of complex cases during virtual molecular tumor board meetings. Overall, streamlined digital systems like the MTBP are crucial to better address the challenges brought by precision oncology and accelerate the use of emerging biomarkers.

Errataetall:

ErratumIn: Nat Cancer. 2022 May;3(5):649. - PMID 35449310

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:3

Enthalten in:

Nature cancer - 3(2022), 2 vom: 22. Feb., Seite 251-261

Sprache:

Englisch

Beteiligte Personen:

Tamborero, David [VerfasserIn]
Dienstmann, Rodrigo [VerfasserIn]
Rachid, Maan Haj [VerfasserIn]
Boekel, Jorrit [VerfasserIn]
Lopez-Fernandez, Adria [VerfasserIn]
Jonsson, Markus [VerfasserIn]
Razzak, Ali [VerfasserIn]
Braña, Irene [VerfasserIn]
De Petris, Luigi [VerfasserIn]
Yachnin, Jeffrey [VerfasserIn]
Baird, Richard D [VerfasserIn]
Loriot, Yohann [VerfasserIn]
Massard, Christophe [VerfasserIn]
Martin-Romano, Patricia [VerfasserIn]
Opdam, Frans [VerfasserIn]
Schlenk, Richard F [VerfasserIn]
Vernieri, Claudio [VerfasserIn]
Masucci, Michele [VerfasserIn]
Villalobos, Xenia [VerfasserIn]
Chavarria, Elena [VerfasserIn]
Cancer Core Europe consortium [VerfasserIn]
Balmaña, Judith [VerfasserIn]
Apolone, Giovanni [VerfasserIn]
Caldas, Carlos [VerfasserIn]
Bergh, Jonas [VerfasserIn]
Ernberg, Ingemar [VerfasserIn]
Fröhling, Stefan [VerfasserIn]
Garralda, Elena [VerfasserIn]
Karlsson, Claes [VerfasserIn]
Tabernero, Josep [VerfasserIn]
Voest, Emile [VerfasserIn]
Rodon, Jordi [VerfasserIn]
Lehtiö, Janne [VerfasserIn]
Anand, Shubha [Sonstige Person]
Baars, Danny [Sonstige Person]
Bajalica-Lagercrantz, Svetlana [Sonstige Person]
Baird, Richard [Sonstige Person]
Bierkens, Mariska [Sonstige Person]
Blomqvist, Lennart [Sonstige Person]
Bono, Costanza [Sonstige Person]
De Petris, Luigi [Sonstige Person]
Doherty, Gary J [Sonstige Person]
Forest, Arnauld [Sonstige Person]
Fornerone, Valentina [Sonstige Person]
Gabaldi, Paola [Sonstige Person]
Haglund, Felix [Sonstige Person]
Hartman, Johan [Sonstige Person]
Horak, Peter [Sonstige Person]
Jutzi, Tanja [Sonstige Person]
Kasanicki, Mary [Sonstige Person]
Kreutzfeldt, Simon [Sonstige Person]
Le Cornet, Lucian [Sonstige Person]
Lewensohn, Rolf [Sonstige Person]
Lindberg, Johan [Sonstige Person]
Lopez, Carlos [Sonstige Person]
Lundqvist, Andreas [Sonstige Person]
Martin, Jose-Ezequiel [Sonstige Person]
Meijer, Gerrit [Sonstige Person]
Muñoz, Susana [Sonstige Person]
Camus, Maud Ngo [Sonstige Person]
Nicotra, Claudio [Sonstige Person]
Nuciforo, Paolo [Sonstige Person]
Oberrauch, Petra [Sonstige Person]
Östling, Päivi [Sonstige Person]
Pelz, Laura [Sonstige Person]
Piris-Gimenez, Alejandro [Sonstige Person]
Provenzano, Elena [Sonstige Person]
Rouleau, Etienne [Sonstige Person]
Rowell, John [Sonstige Person]
Saavedra, Omar [Sonstige Person]
Scoazec, Giovanni [Sonstige Person]
Seamon, Kenneth [Sonstige Person]
Tischkowitz, Marc [Sonstige Person]
van der Kolk, Lizet [Sonstige Person]
van der Noll, Ruud [Sonstige Person]
Vieito, Maria [Sonstige Person]
Vis, Daniel [Sonstige Person]
Vivancos, Ana [Sonstige Person]
von Gertten, Christina [Sonstige Person]
Wennborg, Anders [Sonstige Person]
Wessels, Lodewyk [Sonstige Person]
Wirta, Valtteri [Sonstige Person]

Links:

Volltext

Themen:

Journal Article
Research Support, Non-U.S. Gov't

Anmerkungen:

Date Completed 19.04.2022

Date Revised 10.02.2024

published: Print-Electronic

ErratumIn: Nat Cancer. 2022 May;3(5):649. - PMID 35449310

Citation Status MEDLINE

doi:

10.1038/s43018-022-00332-x

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM337528039