Preoperative Risk Factors Affecting Outcome in Surgically Treated Pyogenic Spondylodiscitis
STUDY DESIGN: Retrospective study.
OBJECTIVE: The primary aim of this study was to investigate the predictors of severe complications in patients following surgery for pyogenic spondylodiscitis (PS) using a surgeon-maintained database. The secondary aim was to investigate the predictors of early recovery.
METHODS: We introduced a surgeon-maintained database of prospectively collected multicenter data that mainly focused on perioperative complications in 2012. Our surgeon-maintained database allows the retrospective collection of detailed data. We analyzed 143 patients who underwent surgery for PS from the 19,056 patients in the prospective surgeon-maintained database at 27 affiliated institutions between 2013 and 2017. Data relating to preoperative patient factors, infection factors, surgical factors, and pre- and postoperative blood tests was retrospectively collected. We performed multivariate regression analysis to evaluate the predictors of postoperative severe complications and early recovery in patients with PS.
RESULTS: High updated Charlson comorbidity index (uCCI), chronic pulmonary disease, diabetes, Gram-negative bacteria, pyogenic osteoarthritis, high preoperative white blood cell count, and low preoperative platelet count were significantly associated with severe complications in patients undergoing surgery for PS. A high uCCI was the sole independent negative predictor on early recovery.
CONCLUSION: Careful perioperative management is necessary if surgery is performed on patients who are at a high risk of life-threatening events.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2023 |
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| Erschienen: |
2023 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:13 |
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| Enthalten in: |
Global spine journal - 13(2023), 8 vom: 20. Okt., Seite 2201-2209 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Ukon, Yuichiro [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Revised 03.10.2023 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1177/21925682221077918 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM337271267 |
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| 500 | |a Date Revised 03.10.2023 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a STUDY DESIGN: Retrospective study | ||
| 520 | |a OBJECTIVE: The primary aim of this study was to investigate the predictors of severe complications in patients following surgery for pyogenic spondylodiscitis (PS) using a surgeon-maintained database. The secondary aim was to investigate the predictors of early recovery | ||
| 520 | |a METHODS: We introduced a surgeon-maintained database of prospectively collected multicenter data that mainly focused on perioperative complications in 2012. Our surgeon-maintained database allows the retrospective collection of detailed data. We analyzed 143 patients who underwent surgery for PS from the 19,056 patients in the prospective surgeon-maintained database at 27 affiliated institutions between 2013 and 2017. Data relating to preoperative patient factors, infection factors, surgical factors, and pre- and postoperative blood tests was retrospectively collected. We performed multivariate regression analysis to evaluate the predictors of postoperative severe complications and early recovery in patients with PS | ||
| 520 | |a RESULTS: High updated Charlson comorbidity index (uCCI), chronic pulmonary disease, diabetes, Gram-negative bacteria, pyogenic osteoarthritis, high preoperative white blood cell count, and low preoperative platelet count were significantly associated with severe complications in patients undergoing surgery for PS. A high uCCI was the sole independent negative predictor on early recovery | ||
| 520 | |a CONCLUSION: Careful perioperative management is necessary if surgery is performed on patients who are at a high risk of life-threatening events | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Takenaka, Shota |e verfasserin |4 aut | |
| 700 | 1 | |a Makino, Takahiro |e verfasserin |4 aut | |
| 700 | 1 | |a Kashii, Masafumi |e verfasserin |4 aut | |
| 700 | 1 | |a Iwasaki, Motoki |e verfasserin |4 aut | |
| 700 | 1 | |a Sakai, Yusuke |e verfasserin |4 aut | |
| 700 | 1 | |a Inoue, Takuya |e verfasserin |4 aut | |
| 700 | 1 | |a Ishiguro, Hiroyuki |e verfasserin |4 aut | |
| 700 | 1 | |a Kaito, Takashi |e verfasserin |4 aut | |
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