An update on dapagliflozin for chronic kidney disease

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Dapagliflozin is an oral agent for type 2 diabetes mellitus (T2DM) belonging to the sodium/glucose cotransporter 2 inhibitor (SGLT2-I) class of antihyperglycemic medications. In clinical trials, dapagliflozin has also been shown to reduce cardiovascular and major renal events. In the DAPA-CKD trial, dapagliflozin significantly reduced the composite renal outcome in patients with chronic kidney disease (CKD). Dapagliflozin represents a new pharmacologic option for reducing CKD progression in patients with and without diabetes.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:58

Enthalten in:

Drugs of today (Barcelona, Spain : 1998) - 58(2022), 2 vom: 04. Feb., Seite 69-75

Sprache:

Englisch

Beteiligte Personen:

Kelly, Michael S [VerfasserIn]

Links:

Volltext

Themen:

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Chronic kidney disease
Dapagliflozin
Diabetes
Journal Article
Nephropathy
Renal disorders
Sodium/glucose cotransporter 2 (SGLT2) inhibitors
Sodium-Glucose Transporter 2 Inhibitors

Anmerkungen:

Date Completed 22.02.2022

Date Revised 31.05.2022

published: Print

Citation Status MEDLINE

doi:

10.1358/dot.2022.58.2.3369188

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM337199671