COVID-19 Vaccine-Induced Multisystem Inflammatory Syndrome With Polyserositis Detected by FDG PET/CT
Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved..
ABSTRACT: Of the various adverse reactions to COVID-19 vaccines, fever is a common systemic symptom that often resolves spontaneously without treatment. However, rare vaccine-induced conditions that present with fever and systemic inflammation have been reported. In this case, a 65-year-old man with BNT162b2 mRNA COVID-19 vaccination underwent 18F-FDG PET/CT to evaluate prolonged fever and elevated serum C-reactive protein. PET/CT showed hypermetabolic infiltration in the pericardium and peritoneum suggesting immune-mediated pericarditis and peritonitis. After administration of high-dose corticosteroids, the patient's symptom resolved. This case suggests that multisystem inflammatory syndrome and polyserositis can be induced by the COVID-19 vaccine.
| Errataetall: |
CommentIn: Clin Nucl Med. 2022 Nov 1;47(11):e723. - PMID 35485865 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:47 |
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| Enthalten in: |
Clinical nuclear medicine - 47(2022), 5 vom: 01. Mai, Seite e397-e398 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Lee, Soo Jin [VerfasserIn] |
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| Links: |
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| Themen: |
0Z5B2CJX4D |
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| Anmerkungen: |
Date Completed 07.04.2022 Date Revised 25.09.2023 published: Print CommentIn: Clin Nucl Med. 2022 Nov 1;47(11):e723. - PMID 35485865 Citation Status MEDLINE |
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| doi: |
10.1097/RLU.0000000000004094 |
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| funding: |
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| 520 | |a ABSTRACT: Of the various adverse reactions to COVID-19 vaccines, fever is a common systemic symptom that often resolves spontaneously without treatment. However, rare vaccine-induced conditions that present with fever and systemic inflammation have been reported. In this case, a 65-year-old man with BNT162b2 mRNA COVID-19 vaccination underwent 18F-FDG PET/CT to evaluate prolonged fever and elevated serum C-reactive protein. PET/CT showed hypermetabolic infiltration in the pericardium and peritoneum suggesting immune-mediated pericarditis and peritonitis. After administration of high-dose corticosteroids, the patient's symptom resolved. This case suggests that multisystem inflammatory syndrome and polyserositis can be induced by the COVID-19 vaccine | ||
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