The association of breastfeeding and other factors on respiratory virus positivity and severity in hospitalized children
© 2022 The Societies and John Wiley & Sons Australia, Ltd..
Acute respiratory infections (ARIs) are the most prevalent diseases in children under 5 years old, and viruses are the leading cause. ARIs arise due to numerous factors, including age, contact with siblings or other children in daycare centers, and environmental pollution. Breastfeeding reportedly confers protection against ARIs through bioactive components related to mucous epithelial immunity. This study aimed to evaluate the frequency and severity of viral ARIs in hospitalized children, together with the status and duration of exclusive breastfeeding (EBF) and other associated factors. It comprised an epidemiological surveillance study to investigate respiratory viruses in hospitalized children, in which demographic and clinical data were collected. Overall, 279 patients were included, 190 (68%) had positive viral results, and 132 (47%) were exclusively breastfed. In an adjusted analysis, it was observed that older children, the parents' educational level, and the presence of chronic disease were significantly related to EBF for more than 6 months. No significant differences were observed in viral positivity and disease severity concerning EBF. Whereas the EBF status was associated with a positive rate of virus detection, the significance did not remain after adjustment, and it was not considered a protective factor against ARIs. On the other hand, young age and exposure to tobacco were confirmed as risk factors of frequency and severity, respectively. Such confounding factors can impact the analysis and should be considered in future studies.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:66 |
|---|---|
| Enthalten in: |
Microbiology and immunology - 66(2022), 5 vom: 28. Mai, Seite 216-224 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Ferreira, Laura Holtman [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Breastfeeding |
|---|
| Anmerkungen: |
Date Completed 11.05.2022 Date Revised 11.05.2022 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1111/1348-0421.12969 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM336997124 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM336997124 | ||
| 003 | DE-627 | ||
| 005 | 20231225233419.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1111/1348-0421.12969 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1123.xml |
| 035 | |a (DE-627)NLM336997124 | ||
| 035 | |a (NLM)35167712 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Ferreira, Laura Holtman |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The association of breastfeeding and other factors on respiratory virus positivity and severity in hospitalized children |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 11.05.2022 | ||
| 500 | |a Date Revised 11.05.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2022 The Societies and John Wiley & Sons Australia, Ltd. | ||
| 520 | |a Acute respiratory infections (ARIs) are the most prevalent diseases in children under 5 years old, and viruses are the leading cause. ARIs arise due to numerous factors, including age, contact with siblings or other children in daycare centers, and environmental pollution. Breastfeeding reportedly confers protection against ARIs through bioactive components related to mucous epithelial immunity. This study aimed to evaluate the frequency and severity of viral ARIs in hospitalized children, together with the status and duration of exclusive breastfeeding (EBF) and other associated factors. It comprised an epidemiological surveillance study to investigate respiratory viruses in hospitalized children, in which demographic and clinical data were collected. Overall, 279 patients were included, 190 (68%) had positive viral results, and 132 (47%) were exclusively breastfed. In an adjusted analysis, it was observed that older children, the parents' educational level, and the presence of chronic disease were significantly related to EBF for more than 6 months. No significant differences were observed in viral positivity and disease severity concerning EBF. Whereas the EBF status was associated with a positive rate of virus detection, the significance did not remain after adjustment, and it was not considered a protective factor against ARIs. On the other hand, young age and exposure to tobacco were confirmed as risk factors of frequency and severity, respectively. Such confounding factors can impact the analysis and should be considered in future studies | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a breastfeeding | |
| 650 | 4 | |a epidemiologic surveillance | |
| 650 | 4 | |a respiratory virus | |
| 650 | 4 | |a syncytial respiratory virus | |
| 700 | 1 | |a Silva, Breno Gonçalves da |e verfasserin |4 aut | |
| 700 | 1 | |a Giamberardino, Heloísa Ihle |e verfasserin |4 aut | |
| 700 | 1 | |a Pacheco, Ana Paula |e verfasserin |4 aut | |
| 700 | 1 | |a Pereira, Luciane Aparecida |e verfasserin |4 aut | |
| 700 | 1 | |a Genelhoud, Gustavo |e verfasserin |4 aut | |
| 700 | 1 | |a Petterle, Ricardo Rasmussen |e verfasserin |4 aut | |
| 700 | 1 | |a Raboni, Sonia Mara |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Microbiology and immunology |d 1979 |g 66(2022), 5 vom: 28. Mai, Seite 216-224 |w (DE-627)NLM000170208 |x 1348-0421 |7 nnns |
| 773 | 1 | 8 | |g volume:66 |g year:2022 |g number:5 |g day:28 |g month:05 |g pages:216-224 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1111/1348-0421.12969 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 66 |j 2022 |e 5 |b 28 |c 05 |h 216-224 | ||