The Use of Wearable Pulse Oximeters in the Prompt Detection of Hypoxemia and During Movement : Diagnostic Accuracy Study
©Mauro Santos, Sarah Vollam, Marco AF Pimentel, Carlos Areia, Louise Young, Cristian Roman, Jody Ede, Philippa Piper, Elizabeth King, Mirae Harford, Akshay Shah, Owen Gustafson, Lionel Tarassenko, Peter Watkinson. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 15.02.2022..
BACKGROUND: Commercially available wearable (ambulatory) pulse oximeters have been recommended as a method for managing patients at risk of physiological deterioration, such as active patients with COVID-19 disease receiving care in hospital isolation rooms; however, their reliability in usual hospital settings is not known.
OBJECTIVE: We report the performance of wearable pulse oximeters in a simulated clinical setting when challenged by motion and low levels of arterial blood oxygen saturation (SaO2).
METHODS: The performance of 1 wrist-worn (Wavelet) and 3 finger-worn (CheckMe O2+, AP-20, and WristOx2 3150) wearable, wireless transmission-mode pulse oximeters was evaluated. For this, 7 motion tasks were performed: at rest, sit-to-stand, tapping, rubbing, drinking, turning pages, and using a tablet. Hypoxia exposure followed, in which inspired gases were adjusted to achieve decreasing SaO2 levels at 100%, 95%, 90%, 87%, 85%, 83%, and 80%. Peripheral oxygen saturation (SpO2) estimates were compared with simultaneous SaO2 samples to calculate the root-mean-square error (RMSE). The area under the receiver operating characteristic curve was used to analyze the detection of hypoxemia (ie, SaO2<90%).
RESULTS: SpO2 estimates matching 215 SaO2 samples in both study phases, from 33 participants, were analyzed. Tapping, rubbing, turning pages, and using a tablet degraded SpO2 estimation (RMSE>4% for at least 1 device). All finger-worn pulse oximeters detected hypoxemia, with an overall sensitivity of ≥0.87 and specificity of ≥0.80, comparable to that of the Philips MX450 pulse oximeter.
CONCLUSIONS: The SpO2 accuracy of wearable finger-worn pulse oximeters was within that required by the International Organization for Standardization guidelines. Performance was degraded by motion, but all pulse oximeters could detect hypoxemia. Our findings support the use of wearable, wireless transmission-mode pulse oximeters to detect the onset of clinical deterioration in hospital settings.
TRIAL REGISTRATION: ISRCTN Registry 61535692; http://www.isrctn.com/ISRCTN61535692.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.1136/bmjopen-2019-034404.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2022 |
|---|---|
| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:24 |
|---|---|
| Enthalten in: |
Journal of medical Internet research - 24(2022), 2 vom: 15. Feb., Seite e28890 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Santos, Mauro [VerfasserIn] |
|---|
| Links: |
|---|
| Anmerkungen: |
Date Completed 18.02.2022 Date Revised 16.07.2022 published: Electronic ISRCTN: ISRCTN61535692 Citation Status MEDLINE |
|---|
| doi: |
10.2196/28890 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM33698748X |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM33698748X | ||
| 003 | DE-627 | ||
| 005 | 20231225233406.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2022 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.2196/28890 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1123.xml |
| 035 | |a (DE-627)NLM33698748X | ||
| 035 | |a (NLM)35166690 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Santos, Mauro |e verfasserin |4 aut | |
| 245 | 1 | 4 | |a The Use of Wearable Pulse Oximeters in the Prompt Detection of Hypoxemia and During Movement |b Diagnostic Accuracy Study |
| 264 | 1 | |c 2022 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 18.02.2022 | ||
| 500 | |a Date Revised 16.07.2022 | ||
| 500 | |a published: Electronic | ||
| 500 | |a ISRCTN: ISRCTN61535692 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a ©Mauro Santos, Sarah Vollam, Marco AF Pimentel, Carlos Areia, Louise Young, Cristian Roman, Jody Ede, Philippa Piper, Elizabeth King, Mirae Harford, Akshay Shah, Owen Gustafson, Lionel Tarassenko, Peter Watkinson. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 15.02.2022. | ||
| 520 | |a BACKGROUND: Commercially available wearable (ambulatory) pulse oximeters have been recommended as a method for managing patients at risk of physiological deterioration, such as active patients with COVID-19 disease receiving care in hospital isolation rooms; however, their reliability in usual hospital settings is not known | ||
| 520 | |a OBJECTIVE: We report the performance of wearable pulse oximeters in a simulated clinical setting when challenged by motion and low levels of arterial blood oxygen saturation (SaO2) | ||
| 520 | |a METHODS: The performance of 1 wrist-worn (Wavelet) and 3 finger-worn (CheckMe O2+, AP-20, and WristOx2 3150) wearable, wireless transmission-mode pulse oximeters was evaluated. For this, 7 motion tasks were performed: at rest, sit-to-stand, tapping, rubbing, drinking, turning pages, and using a tablet. Hypoxia exposure followed, in which inspired gases were adjusted to achieve decreasing SaO2 levels at 100%, 95%, 90%, 87%, 85%, 83%, and 80%. Peripheral oxygen saturation (SpO2) estimates were compared with simultaneous SaO2 samples to calculate the root-mean-square error (RMSE). The area under the receiver operating characteristic curve was used to analyze the detection of hypoxemia (ie, SaO2<90%) | ||
| 520 | |a RESULTS: SpO2 estimates matching 215 SaO2 samples in both study phases, from 33 participants, were analyzed. Tapping, rubbing, turning pages, and using a tablet degraded SpO2 estimation (RMSE>4% for at least 1 device). All finger-worn pulse oximeters detected hypoxemia, with an overall sensitivity of ≥0.87 and specificity of ≥0.80, comparable to that of the Philips MX450 pulse oximeter | ||
| 520 | |a CONCLUSIONS: The SpO2 accuracy of wearable finger-worn pulse oximeters was within that required by the International Organization for Standardization guidelines. Performance was degraded by motion, but all pulse oximeters could detect hypoxemia. Our findings support the use of wearable, wireless transmission-mode pulse oximeters to detect the onset of clinical deterioration in hospital settings | ||
| 520 | |a TRIAL REGISTRATION: ISRCTN Registry 61535692; http://www.isrctn.com/ISRCTN61535692 | ||
| 520 | |a INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.1136/bmjopen-2019-034404 | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a blood oxygen | |
| 650 | 4 | |a continuous monitoring | |
| 650 | 4 | |a deterioration | |
| 650 | 4 | |a diagnostic accuracy | |
| 650 | 4 | |a hospital | |
| 650 | 4 | |a hypoxemia | |
| 650 | 4 | |a hypoxia | |
| 650 | 4 | |a mHealth | |
| 650 | 4 | |a patient monitoring | |
| 650 | 4 | |a wearable pulse oximeter | |
| 650 | 4 | |a wearable technology | |
| 700 | 1 | |a Vollam, Sarah |e verfasserin |4 aut | |
| 700 | 1 | |a Pimentel, Marco Af |e verfasserin |4 aut | |
| 700 | 1 | |a Areia, Carlos |e verfasserin |4 aut | |
| 700 | 1 | |a Young, Louise |e verfasserin |4 aut | |
| 700 | 1 | |a Roman, Cristian |e verfasserin |4 aut | |
| 700 | 1 | |a Ede, Jody |e verfasserin |4 aut | |
| 700 | 1 | |a Piper, Philippa |e verfasserin |4 aut | |
| 700 | 1 | |a King, Elizabeth |e verfasserin |4 aut | |
| 700 | 1 | |a Harford, Mirae |e verfasserin |4 aut | |
| 700 | 1 | |a Shah, Akshay |e verfasserin |4 aut | |
| 700 | 1 | |a Gustafson, Owen |e verfasserin |4 aut | |
| 700 | 1 | |a Tarassenko, Lionel |e verfasserin |4 aut | |
| 700 | 1 | |a Watkinson, Peter |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Journal of medical Internet research |d 1999 |g 24(2022), 2 vom: 15. Feb., Seite e28890 |w (DE-627)NLM116127104 |x 1438-8871 |7 nnns |
| 773 | 1 | 8 | |g volume:24 |g year:2022 |g number:2 |g day:15 |g month:02 |g pages:e28890 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.2196/28890 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 24 |j 2022 |e 2 |b 15 |c 02 |h e28890 | ||