Ultrasound-guided genicular nerve block versus physical therapy for chronic knee osteoarthritis : a prospective randomised study
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature..
To compare the effectiveness of ultrasound-guided genicular nerve block (GNB) and physical therapy (PT) in patients with chronic knee osteoarthritis. A prospective randomised study with 102 patients (45-70 years) was performed wherein the patients received ultrasound-guided GNB (n = 51) and PT (n = 51) along with a standard home exercise programme. Scores for pain on a Visual Analogue Scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and 6-min walking test (6MWT) were assessed pre-treatment and at 2- and 12-weeks post-treatment. Both groups were comparable for sociodemographic characteristics. VAS scores (in mm) in the ultrasound-guided GNB group at 0, 2 and 12 weeks were 7.01 ± 1.36; 3.71 ± 2.18; 5.08 ± 2.22 (p < 0.001) and 6.64 ± 1.99; 4.35 ± 1.09; 5.25 ± 1.33, (p < 0.001) in the PT group. While the increase in the 6MWT test in the 2nd week was similar for both groups (p = 0.073), the increase in walking distance was greater in the ultrasound-guided GNB group at 12 weeks (p = 0.046). As compared to PT, ultrasound-guided GNB is beneficial in reducing pain and increasing functional and physical capacity, with greater retention of effects on the physical capacity seen at 12 weeks. Trial registration number: ClinicalTrials.gov (NCT04782401).
| Errataetall: |
CommentIn: Rheumatol Int. 2022 Sep;42(9):1663-1664. - PMID 35713678 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:42 |
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| Enthalten in: |
Rheumatology international - 42(2022), 4 vom: 14. Apr., Seite 591-600 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Güler, Tuba [VerfasserIn] |
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| Links: |
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| Themen: |
Journal Article |
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| Anmerkungen: |
Date Completed 18.04.2022 Date Revised 16.08.2022 published: Print-Electronic ClinicalTrials.gov: NCT04782401 CommentIn: Rheumatol Int. 2022 Sep;42(9):1663-1664. - PMID 35713678 Citation Status MEDLINE |
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| doi: |
10.1007/s00296-022-05101-8 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM336978537 |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. | ||
| 520 | |a To compare the effectiveness of ultrasound-guided genicular nerve block (GNB) and physical therapy (PT) in patients with chronic knee osteoarthritis. A prospective randomised study with 102 patients (45-70 years) was performed wherein the patients received ultrasound-guided GNB (n = 51) and PT (n = 51) along with a standard home exercise programme. Scores for pain on a Visual Analogue Scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and 6-min walking test (6MWT) were assessed pre-treatment and at 2- and 12-weeks post-treatment. Both groups were comparable for sociodemographic characteristics. VAS scores (in mm) in the ultrasound-guided GNB group at 0, 2 and 12 weeks were 7.01 ± 1.36; 3.71 ± 2.18; 5.08 ± 2.22 (p < 0.001) and 6.64 ± 1.99; 4.35 ± 1.09; 5.25 ± 1.33, (p < 0.001) in the PT group. While the increase in the 6MWT test in the 2nd week was similar for both groups (p = 0.073), the increase in walking distance was greater in the ultrasound-guided GNB group at 12 weeks (p = 0.046). As compared to PT, ultrasound-guided GNB is beneficial in reducing pain and increasing functional and physical capacity, with greater retention of effects on the physical capacity seen at 12 weeks. Trial registration number: ClinicalTrials.gov (NCT04782401) | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Randomized Controlled Trial | |
| 650 | 4 | |a Knee joint | |
| 650 | 4 | |a Nerve block | |
| 650 | 4 | |a Osteoarthritis | |
| 650 | 4 | |a Physical therapy modalities | |
| 650 | 4 | |a Ultrasound | |
| 700 | 1 | |a Yurdakul, Fatma Gül |e verfasserin |4 aut | |
| 700 | 1 | |a Önder, Mustafa Erkut |e verfasserin |4 aut | |
| 700 | 1 | |a Erdoğan, Faruk |e verfasserin |4 aut | |
| 700 | 1 | |a Yavuz, Kaan |e verfasserin |4 aut | |
| 700 | 1 | |a Becenen, Elif |e verfasserin |4 aut | |
| 700 | 1 | |a Uçkun, Aslı |e verfasserin |4 aut | |
| 700 | 1 | |a Bodur, Hatice |e verfasserin |4 aut | |
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