Genetic integration of behavioural and endocrine components of the stress response
© 2022, Houslay et al..
The vertebrate stress response comprises a suite of behavioural and physiological traits that must be functionally integrated to ensure organisms cope adaptively with acute stressors. Natural selection should favour functional integration, leading to a prediction of genetic integration of these traits. Despite the implications of such genetic integration for our understanding of human and animal health, as well as evolutionary responses to natural and anthropogenic stressors, formal quantitative genetic tests of this prediction are lacking. Here, we demonstrate that acute stress response components in Trinidadian guppies are both heritable and integrated on the major axis of genetic covariation. This integration could either facilitate or constrain evolutionary responses to selection, depending upon the alignment of selection with this axis. Such integration also suggests artificial selection on the genetically correlated behavioural responses to stress could offer a viable non-invasive route to the improvement of health and welfare in captive animal populations.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:11 |
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| Enthalten in: |
eLife - 11(2022) vom: 11. Feb. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Houslay, Thomas M [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 22.02.2022 Date Revised 22.02.2022 published: Electronic Dryad: 10.5061/dryad.z34tmpgcg Citation Status MEDLINE |
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| doi: |
10.7554/eLife.67126 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a The vertebrate stress response comprises a suite of behavioural and physiological traits that must be functionally integrated to ensure organisms cope adaptively with acute stressors. Natural selection should favour functional integration, leading to a prediction of genetic integration of these traits. Despite the implications of such genetic integration for our understanding of human and animal health, as well as evolutionary responses to natural and anthropogenic stressors, formal quantitative genetic tests of this prediction are lacking. Here, we demonstrate that acute stress response components in Trinidadian guppies are both heritable and integrated on the major axis of genetic covariation. This integration could either facilitate or constrain evolutionary responses to selection, depending upon the alignment of selection with this axis. Such integration also suggests artificial selection on the genetically correlated behavioural responses to stress could offer a viable non-invasive route to the improvement of health and welfare in captive animal populations | ||
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| 650 | 4 | |a coping styles | |
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| 700 | 1 | |a Lammers, Wiebke |e verfasserin |4 aut | |
| 700 | 1 | |a Grimmer, Andrew J |e verfasserin |4 aut | |
| 700 | 1 | |a Travers, Laura M |e verfasserin |4 aut | |
| 700 | 1 | |a Johnson, Elizabeth L |e verfasserin |4 aut | |
| 700 | 1 | |a Young, Andrew J |e verfasserin |4 aut | |
| 700 | 1 | |a Wilson, Alastair |e verfasserin |4 aut | |
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