Thioethers : An Overview

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Spreading rapidly in recent years, cancer has become one of the causes of the highest mortality rates after cardiovascular diseases. The reason for cancer development is still not clearly understood despite enormous research activities in this area. Scientists are now working on the biology of cancer, especially on the root cause of cancer development. The aim is to treat the cancer disease and thus cure the patients. The continuing efforts for the development of novel molecules as potential anti-cancer agents are essential for this purpose. The main aim of this review was to present a survey on the medicinal chemistry of thioethers and provide practical data on their cytotoxicities against various cancer cell lines. The research articles published between 2001-2020 were consulted to prepare this review article; however, patent literature has not been included. The thioether-containing heterocyclic compounds may emerge as a new class of potent and effective anti-cancer agents in the future.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:23

Enthalten in:

Current drug targets - 23(2022), 2 vom: 31., Seite 170-219

Sprache:

Englisch

Beteiligte Personen:

Han, M İhsan [VerfasserIn]
Küçükgüzel, Ş Güniz [VerfasserIn]

Links:

Volltext

Themen:

Anticancer activity
Antineoplastic
Antineoplastic Agents
Cardiovascular diseases.
Cytotoxicity
Heterocyclic Compounds
Journal Article
Pharmacokinetics
Review
Sulfides
Thioether

Anmerkungen:

Date Completed 02.05.2022

Date Revised 02.05.2022

published: Print

Citation Status MEDLINE

doi:

10.2174/1389450122666210614121237

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM336720564