Pathological effects of SARS-CoV-2 on hematological and immunological cells : Alterations in count, morphology, and function
Copyright © 2022 Elsevier GmbH. All rights reserved..
The novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), the causative agent of COVID-19 outbreak, spread rapidly and infected more than 140 million people with more than three million victims worldwide. The SARS-CoV-2 causes destructive changes in the immunological and hematological system of the host. These alterations appear to play a critical role in disease pathology and the emerging of clinical manifestations. In this review, we aimed to discuss the effect of COVID-19 on the count, function and morphology of immune and blood cells and the role of these changes in the pathophysiology of the disease. Knowledge of these changes may help with better management and treatment of COVID-19 patients.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2022 |
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Erschienen: |
2022 |
Enthalten in: |
Zur Gesamtaufnahme - volume:231 |
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Enthalten in: |
Pathology, research and practice - 231(2022) vom: 01. März, Seite 153782 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Ahmadi, Ehsan [VerfasserIn] |
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Links: |
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Themen: |
Blood platelets |
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Anmerkungen: |
Date Completed 16.03.2022 Date Revised 14.02.2023 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1016/j.prp.2022.153782 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM336539096 |
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520 | |a The novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), the causative agent of COVID-19 outbreak, spread rapidly and infected more than 140 million people with more than three million victims worldwide. The SARS-CoV-2 causes destructive changes in the immunological and hematological system of the host. These alterations appear to play a critical role in disease pathology and the emerging of clinical manifestations. In this review, we aimed to discuss the effect of COVID-19 on the count, function and morphology of immune and blood cells and the role of these changes in the pathophysiology of the disease. Knowledge of these changes may help with better management and treatment of COVID-19 patients | ||
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