Pathological effects of SARS-CoV-2 on hematological and immunological cells : Alterations in count, morphology, and function

Copyright © 2022 Elsevier GmbH. All rights reserved..

The novel Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), the causative agent of COVID-19 outbreak, spread rapidly and infected more than 140 million people with more than three million victims worldwide. The SARS-CoV-2 causes destructive changes in the immunological and hematological system of the host. These alterations appear to play a critical role in disease pathology and the emerging of clinical manifestations. In this review, we aimed to discuss the effect of COVID-19 on the count, function and morphology of immune and blood cells and the role of these changes in the pathophysiology of the disease. Knowledge of these changes may help with better management and treatment of COVID-19 patients.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:231

Enthalten in:

Pathology, research and practice - 231(2022) vom: 01. März, Seite 153782

Sprache:

Englisch

Beteiligte Personen:

Ahmadi, Ehsan [VerfasserIn]
Bagherpour, Zahra [VerfasserIn]
Zarei, Elmira [VerfasserIn]
Omidkhoda, Azadeh [VerfasserIn]

Links:

Volltext

Themen:

Blood platelets
Erythrocytes
Granulocytes
Immunity
Journal Article
Monocytes
Review
SARS-COV-2

Anmerkungen:

Date Completed 16.03.2022

Date Revised 14.02.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.prp.2022.153782

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM336539096