Selection of natural biomaterials for micro-tissue and organ-on-chip models
© 2022 Wiley Periodicals LLC..
The desired organ in micro-tissue models of organ-on-a-chip (OoC) devices dictates the optimum biomaterials, divided into natural and synthetic biomaterials. They can resemble biological tissues' biological functions and architectures by constructing bioactivity of macromolecules, cells, nanoparticles, and other biological agents. The inclusion of such components in OoCs allows them having biological processes, such as basic biorecognition, enzymatic cleavage, and regulated drug release. In this report, we review natural-based biomaterials that are used in OoCs and their main characteristics. We address the preparation, modification, and characterization methods of natural-based biomaterials and summarize recent reports on their applications in the design and fabrication of micro-tissue models. This article will help bioengineers select the proper biomaterials based on developing new technologies to meet clinical expectations and improve patient outcomes fusing disease modeling.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2022 |
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Erschienen: |
2022 |
Enthalten in: |
Zur Gesamtaufnahme - volume:110 |
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Enthalten in: |
Journal of biomedical materials research. Part A - 110(2022), 5 vom: 15. Mai, Seite 1147-1165 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Cecen, Berivan [VerfasserIn] |
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Links: |
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Themen: |
Biocompatible Materials |
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Anmerkungen: |
Date Completed 25.04.2022 Date Revised 08.12.2023 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1002/jbm.a.37353 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM336363869 |
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