Increased risk of infection with SARS-CoV-2 Omicron BA.1 compared with Delta in vaccinated and previously infected individuals, the Netherlands, 22 November 2021 to 19 January 2022
Infections with the Omicron SARS-CoV-2 variant are rapidly increasing worldwide. Among 174,349 SARS-CoV-2-infected individuals (≥ 12 years), we observed an increased risk of S gene target failure, predictive of the Omicron variant, in vaccinated (odds ratio (OR): 3.6; 95% confidence interval (CI): 3.4-3.7) and previously infected individuals (OR: 4.2; 95% CI: 3.8-4.7) compared with infected naïve individuals. This suggests vaccine- or infection-induced immunity against SARS-CoV-2 infections is less effective against the Omicron than the Delta variant.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2022 |
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| Erschienen: |
2022 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:27 |
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| Enthalten in: |
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin - 27(2022), 4 vom: 28. Jan. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Eggink, Dirk [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 01.02.2022 Date Revised 17.09.2023 published: Print Citation Status MEDLINE |
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| doi: |
10.2807/1560-7917.ES.2022.27.4.2101196 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM336209681 |
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| 245 | 1 | 0 | |a Increased risk of infection with SARS-CoV-2 Omicron BA.1 compared with Delta in vaccinated and previously infected individuals, the Netherlands, 22 November 2021 to 19 January 2022 |
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| 520 | |a Infections with the Omicron SARS-CoV-2 variant are rapidly increasing worldwide. Among 174,349 SARS-CoV-2-infected individuals (≥ 12 years), we observed an increased risk of S gene target failure, predictive of the Omicron variant, in vaccinated (odds ratio (OR): 3.6; 95% confidence interval (CI): 3.4-3.7) and previously infected individuals (OR: 4.2; 95% CI: 3.8-4.7) compared with infected naïve individuals. This suggests vaccine- or infection-induced immunity against SARS-CoV-2 infections is less effective against the Omicron than the Delta variant | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a SARS-CoV-2 Omicron Variant of Concern Vaccine escape | |
| 650 | 4 | |a air-borne infections | |
| 650 | 4 | |a epidemiology | |
| 650 | 4 | |a laboratory | |
| 650 | 4 | |a severe acute respiratory syndrome - SARS | |
| 650 | 4 | |a vaccines and immunisation | |
| 650 | 4 | |a viral infections | |
| 650 | 7 | |a COVID-19 Vaccines |2 NLM | |
| 700 | 1 | |a Andeweg, Stijn P |e verfasserin |4 aut | |
| 700 | 1 | |a Vennema, Harry |e verfasserin |4 aut | |
| 700 | 1 | |a van Maarseveen, Noortje |e verfasserin |4 aut | |
| 700 | 1 | |a Vermaas, Klaas |e verfasserin |4 aut | |
| 700 | 1 | |a Vlaemynck, Boris |e verfasserin |4 aut | |
| 700 | 1 | |a Schepers, Raf |e verfasserin |4 aut | |
| 700 | 1 | |a van Gageldonk-Lafeber, Arianne B |e verfasserin |4 aut | |
| 700 | 1 | |a van den Hof, Susan |e verfasserin |4 aut | |
| 700 | 1 | |a Reusken, Chantal Bem |e verfasserin |4 aut | |
| 700 | 1 | |a Knol, Mirjam J |e verfasserin |4 aut | |
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